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- W2039410061 abstract "Three cases of neonatal lupus erythematosus (NLE) syndrome are described. The key diagnostic sign is the erythematous and annular clinical appearance of lesions. The histopathologic findings may be subtle in NLE syndrome compared with discoid or subacute cutaneous lupus erythematosus. Direct immunofluorescence testing may be useful in supplementing the histopathologic evaluation. Detection of immunoglobulins, complement, or both at the basement membrane zone in lesional skin by immunofluorescence occurs in approximately half of cases; a negative study does not preclude the diagnosis of NLE syndrome. Clinical and serologic evaluation of both the infant and the mother are important in establishing a diagnosis of NLE syndrome, particularly when histopathologic findings are subtle." @default.
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- W2039410061 date "1991-10-01" @default.
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- W2039410061 title "Neonatal lupus erythematosus syndrome" @default.
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- W2039410061 doi "https://doi.org/10.1111/j.1600-0560.1991.tb01545.x" @default.
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