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- W2039442046 abstract "Objectives: To study psychophysical changes in fibromyalgia and repetitive strain injury, respectively diffuse and regional cervicobrachial musculoskeletal pain syndromes. The clinical phenomena of tenderness [hyperalgesia] in particular but also dysesthesia, paresthesia and motor dysfunction occuring in the absence of tissue damage or disease suggest that altered nociception may be relevant to the pathogenesis of these disorders. Methods: Non-noxious electrocutaneous stimulation in the upper limbs of patients with these syndromes was used as a psychophysican tool. Results: No difference in the threshold for sensory perception but marked reduction in pain threshold and pain tolerance were found in patients compared with control subjects. Furthermore, the electrocutaneous stimulation was accompanied by the spread and persistence of dysesthesia, in painful limbs only. Conclusion: These upper limbs were thus defined psychophysically as well as clinically as regions of secondary hyperalgesia, which may imply that perturbation of central nociceptive mechanisms is involved in the pathogenesis of these syndromes." @default.
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- W2039442046 date "1995-01-01" @default.
- W2039442046 modified "2023-09-26" @default.
- W2039442046 title "Evidence for Abnormal Nociception in Fibromyalgia and Repetitive Strain Injury" @default.
- W2039442046 doi "https://doi.org/10.1300/j094v03n02_07" @default.
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