FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039443534> ?p ?o ?g. }

• W2039443534 endingPage "1964" @default.
• W2039443534 startingPage "1959" @default.
• W2039443534 abstract "With limited treatment options, intraperitoneal spread of ovarian cancer is a common problem leading to high morbidity. Intraperitoneal photodynamic therapy combined with debulking surgery to treat residual disease is an alternative choice for clinicians. Hematoporphyrin monomethyl ether (HMME) is a promising second-generation photosensitizer developed in China. Our study was designed to investigate the phototoxicity of HMME on ovarian cancer. NuTu-19, a cell line derived from adenocarcinoma of Fischer 344 rat, and its allogeneic graft ascites tumor model was used in this study. HMME was confirmed to be localized in cytolysosome, and HMME-based photosensitization induced direct necrosis as well as mitochondria damage. The photocytotoxicity of HMME was both light- and drug dose-dependent and no significant dark cytotoxicity was observed in NuTu-19 cells. With the ascite tumor-bearing Fischer 344 rat model, HMME-based intraperitoneal photodynamic therapy was proved to be useful in improving the prognosis of ovarian cancer. Thus, this study provides evidence that HMME-based photodynamic therapy is an effective adjuvant therapy for ovarian cancer. (Cancer Sci 2007; 98: 1959–1964)" @default.
• W2039443534 created "2016-06-24" @default.
• W2039443534 creator A5012193124 @default.
• W2039443534 creator A5016935464 @default.
• W2039443534 creator A5027475930 @default.
• W2039443534 creator A5046577217 @default.
• W2039443534 creator A5047741217 @default.
• W2039443534 creator A5060155994 @default.
• W2039443534 date "2007-12-01" @default.
• W2039443534 modified "2023-10-10" @default.
• W2039443534 title "Intraperitoneal photodynamic therapy for an ovarian cancer ascite model in Fischer 344 rat using hematoporphyrin monomethyl ether" @default.
• W2039443534 cites W1966434015 @default.
• W2039443534 cites W1970132019 @default.
• W2039443534 cites W1970287836 @default.
• W2039443534 cites W1974712046 @default.
• W2039443534 cites W1979995768 @default.
• W2039443534 cites W1985757402 @default.
• W2039443534 cites W1995751131 @default.
• W2039443534 cites W2000968450 @default.
• W2039443534 cites W2008601705 @default.
• W2039443534 cites W2009828713 @default.
• W2039443534 cites W2015928848 @default.
• W2039443534 cites W2033345397 @default.
• W2039443534 cites W2033571840 @default.
• W2039443534 cites W2042382998 @default.
• W2039443534 cites W2061528142 @default.
• W2039443534 cites W2062797876 @default.
• W2039443534 cites W2102444014 @default.
• W2039443534 cites W2115914766 @default.
• W2039443534 cites W2119393779 @default.
• W2039443534 cites W2120021037 @default.
• W2039443534 cites W2129339346 @default.
• W2039443534 cites W2130866079 @default.
• W2039443534 cites W2135957996 @default.
• W2039443534 cites W2138273429 @default.
• W2039443534 cites W2144314952 @default.
• W2039443534 cites W4246826952 @default.
• W2039443534 doi "https://doi.org/10.1111/j.1349-7006.2007.00628.x" @default.
• W2039443534 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17900310" @default.
• W2039443534 hasPublicationYear "2007" @default.
• W2039443534 type Work @default.
• W2039443534 sameAs 2039443534 @default.
• W2039443534 citedByCount "33" @default.
• W2039443534 countsByYear W20394435342012 @default.
• W2039443534 countsByYear W20394435342013 @default.
• W2039443534 countsByYear W20394435342014 @default.
• W2039443534 countsByYear W20394435342015 @default.
• W2039443534 countsByYear W20394435342016 @default.
• W2039443534 countsByYear W20394435342017 @default.
• W2039443534 countsByYear W20394435342018 @default.
• W2039443534 countsByYear W20394435342019 @default.
• W2039443534 countsByYear W20394435342020 @default.
• W2039443534 countsByYear W20394435342021 @default.
• W2039443534 countsByYear W20394435342022 @default.
• W2039443534 crossrefType "journal-article" @default.
• W2039443534 hasAuthorship W2039443534A5012193124 @default.
• W2039443534 hasAuthorship W2039443534A5016935464 @default.
• W2039443534 hasAuthorship W2039443534A5027475930 @default.
• W2039443534 hasAuthorship W2039443534A5046577217 @default.
• W2039443534 hasAuthorship W2039443534A5047741217 @default.
• W2039443534 hasAuthorship W2039443534A5060155994 @default.
• W2039443534 hasConcept C109316439 @default.
• W2039443534 hasConcept C121608353 @default.
• W2039443534 hasConcept C126322002 @default.
• W2039443534 hasConcept C143998085 @default.
• W2039443534 hasConcept C178790620 @default.
• W2039443534 hasConcept C185592680 @default.
• W2039443534 hasConcept C202751555 @default.
• W2039443534 hasConcept C2780427987 @default.
• W2039443534 hasConcept C2780496750 @default.
• W2039443534 hasConcept C2780699678 @default.
• W2039443534 hasConcept C2781323092 @default.
• W2039443534 hasConcept C2781469039 @default.
• W2039443534 hasConcept C502942594 @default.
• W2039443534 hasConcept C55493867 @default.
• W2039443534 hasConcept C71924100 @default.
• W2039443534 hasConcept C75473681 @default.
• W2039443534 hasConceptScore W2039443534C109316439 @default.
• W2039443534 hasConceptScore W2039443534C121608353 @default.
• W2039443534 hasConceptScore W2039443534C126322002 @default.
• W2039443534 hasConceptScore W2039443534C143998085 @default.
• W2039443534 hasConceptScore W2039443534C178790620 @default.
• W2039443534 hasConceptScore W2039443534C185592680 @default.
• W2039443534 hasConceptScore W2039443534C202751555 @default.
• W2039443534 hasConceptScore W2039443534C2780427987 @default.
• W2039443534 hasConceptScore W2039443534C2780496750 @default.
• W2039443534 hasConceptScore W2039443534C2780699678 @default.
• W2039443534 hasConceptScore W2039443534C2781323092 @default.
• W2039443534 hasConceptScore W2039443534C2781469039 @default.
• W2039443534 hasConceptScore W2039443534C502942594 @default.
• W2039443534 hasConceptScore W2039443534C55493867 @default.
• W2039443534 hasConceptScore W2039443534C71924100 @default.
• W2039443534 hasConceptScore W2039443534C75473681 @default.
• W2039443534 hasIssue "12" @default.
• W2039443534 hasLocation W20394435341 @default.
• W2039443534 hasLocation W20394435342 @default.
• W2039443534 hasOpenAccess W2039443534 @default.
• W2039443534 hasPrimaryLocation W20394435341 @default.

• next