FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039455225> ?p ?o ?g. }

• W2039455225 endingPage "37" @default.
• W2039455225 startingPage "29" @default.
• W2039455225 abstract "The effects of methylenedioxyphenyl insecticide synergists on human health arise, not from their intrinsic toxicity which is relatively low, but from their dual effect on the oxidative detoxication or intoxication processes of the body. They are able to inhibit these reactions by two mechanisms. They are substrates for mixed function oxidation and, thus, compete with other xenobiotics for available enzyme, and an intermediate in their metabolism is able to bind with cytochrome P-450 to form an inactive complex which absorbs maximally at 455 nm. In addition, they are able to activate xenobiotic metabolism by induction (the increased synthesis and retention) of microsomal oxidative enzymes. Evidence for these effects is presented, including spectroscopic and enzyme kinetic data. Correlations with existing in vivo observations are outlined. The inhibition and induction of cytochrome P-450, the central enzyme in the metabolism of xenobiotics, thus provides the focus for consideration of methylenedioxyphenyl synergists as potential hazards." @default.
• W2039455225 created "2016-06-24" @default.
• W2039455225 creator A5054148025 @default.
• W2039455225 date "1976-04-01" @default.
• W2039455225 modified "2023-10-12" @default.
• W2039455225 title "Methylenedioxyphenyl insecticide synergists as potential human health hazards." @default.
• W2039455225 cites W1253386872 @default.
• W2039455225 cites W1496485738 @default.
• W2039455225 cites W1775964807 @default.
• W2039455225 cites W1977175057 @default.
• W2039455225 cites W1977290901 @default.
• W2039455225 cites W1981401471 @default.
• W2039455225 cites W1982640558 @default.
• W2039455225 cites W1984532618 @default.
• W2039455225 cites W1989506902 @default.
• W2039455225 cites W1991284540 @default.
• W2039455225 cites W1991992952 @default.
• W2039455225 cites W1999407399 @default.
• W2039455225 cites W2000030018 @default.
• W2039455225 cites W2000553457 @default.
• W2039455225 cites W2004396786 @default.
• W2039455225 cites W2007945646 @default.
• W2039455225 cites W2026226150 @default.
• W2039455225 cites W2029077217 @default.
• W2039455225 cites W2029986319 @default.
• W2039455225 cites W2031889436 @default.
• W2039455225 cites W2040353978 @default.
• W2039455225 cites W2052134677 @default.
• W2039455225 cites W2066774377 @default.
• W2039455225 cites W2070372890 @default.
• W2039455225 cites W2071165772 @default.
• W2039455225 cites W2074761070 @default.
• W2039455225 cites W2078787199 @default.
• W2039455225 cites W2078918100 @default.
• W2039455225 cites W2085909225 @default.
• W2039455225 cites W2107947237 @default.
• W2039455225 cites W2140484175 @default.
• W2039455225 cites W2147761499 @default.
• W2039455225 cites W2148885238 @default.
• W2039455225 cites W2152320983 @default.
• W2039455225 cites W2404922934 @default.
• W2039455225 cites W2412891865 @default.
• W2039455225 cites W946056603 @default.
• W2039455225 doi "https://doi.org/10.1289/ehp.761429" @default.
• W2039455225 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1475099" @default.
• W2039455225 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/789067" @default.
• W2039455225 hasPublicationYear "1976" @default.
• W2039455225 type Work @default.
• W2039455225 sameAs 2039455225 @default.
• W2039455225 citedByCount "29" @default.
• W2039455225 countsByYear W20394552252012 @default.
• W2039455225 countsByYear W20394552252014 @default.
• W2039455225 countsByYear W20394552252015 @default.
• W2039455225 countsByYear W20394552252022 @default.
• W2039455225 countsByYear W20394552252023 @default.
• W2039455225 crossrefType "journal-article" @default.
• W2039455225 hasAuthorship W2039455225A5054148025 @default.
• W2039455225 hasBestOaLocation W20394552251 @default.
• W2039455225 hasConcept C115448650 @default.
• W2039455225 hasConcept C132154277 @default.
• W2039455225 hasConcept C142724271 @default.
• W2039455225 hasConcept C178790620 @default.
• W2039455225 hasConcept C181199279 @default.
• W2039455225 hasConcept C185592680 @default.
• W2039455225 hasConcept C204787440 @default.
• W2039455225 hasConcept C2777338454 @default.
• W2039455225 hasConcept C2778236027 @default.
• W2039455225 hasConcept C2780497538 @default.
• W2039455225 hasConcept C2780768313 @default.
• W2039455225 hasConcept C29730261 @default.
• W2039455225 hasConcept C33070731 @default.
• W2039455225 hasConcept C526171541 @default.
• W2039455225 hasConcept C55493867 @default.
• W2039455225 hasConcept C57600042 @default.
• W2039455225 hasConcept C62231903 @default.
• W2039455225 hasConcept C62300524 @default.
• W2039455225 hasConcept C71924100 @default.
• W2039455225 hasConcept C86803240 @default.
• W2039455225 hasConcept C87644729 @default.
• W2039455225 hasConcept C89311334 @default.
• W2039455225 hasConceptScore W2039455225C115448650 @default.
• W2039455225 hasConceptScore W2039455225C132154277 @default.
• W2039455225 hasConceptScore W2039455225C142724271 @default.
• W2039455225 hasConceptScore W2039455225C178790620 @default.
• W2039455225 hasConceptScore W2039455225C181199279 @default.
• W2039455225 hasConceptScore W2039455225C185592680 @default.
• W2039455225 hasConceptScore W2039455225C204787440 @default.
• W2039455225 hasConceptScore W2039455225C2777338454 @default.
• W2039455225 hasConceptScore W2039455225C2778236027 @default.
• W2039455225 hasConceptScore W2039455225C2780497538 @default.
• W2039455225 hasConceptScore W2039455225C2780768313 @default.
• W2039455225 hasConceptScore W2039455225C29730261 @default.
• W2039455225 hasConceptScore W2039455225C33070731 @default.
• W2039455225 hasConceptScore W2039455225C526171541 @default.
• W2039455225 hasConceptScore W2039455225C55493867 @default.
• W2039455225 hasConceptScore W2039455225C57600042 @default.
• W2039455225 hasConceptScore W2039455225C62231903 @default.
• W2039455225 hasConceptScore W2039455225C62300524 @default.

• next