FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039455796> ?p ?o ?g. }

• W2039455796 endingPage "3063" @default.
• W2039455796 startingPage "3059" @default.
• W2039455796 abstract "Rats were adrenalectomized and injected for 7 days with dexamethasone (DEX) or deoxycorticosterone. Kallikrein and prekallikrein were assayed in urine and in a basolateral membrane-enriched fraction. The activities of renin and phospholipase A2 were also determined in the fraction. Adrenalectomy significantly decreased active kallikrein in urine. Administration of deoxycorticosterone raised the level of active kallikrein in urine without affecting the concentration of prekallikrein. Rats treated with DEX only had high Na+ and low active kallikrein excretion. The total kallikrein level (active kallikrein together with prekallikrein), however, returned to normal because DEX elevated the prekallikrein level. DEX also increased the prekallikrein concentration in the membrane-enriched fraction. Renin activity in the membrane-enriched fraction was enhanced by adrenalectomy but suppressed by either corticosteroid. The changes in the concentration of plasma renin were qualitatively similar but quantitatively different. The activity of phospholipase A2 in the membrane-enriched fraction was enhanced only by deoxycorticosterone. Thus, both gluco- and mineralocorticoids increased kallikrein excretion in the adrenalectomized animals, but DEX was apparently effective at a lower dose than deoxycorticosterone. DEX increases the prekallikrein concentration in urine and on the basal membrane of distal tubular cells and, in addition, may prevent its conversion by releasing an inhibitor of a prekallikrein activator." @default.
• W2039455796 created "2016-06-24" @default.
• W2039455796 creator A5011486327 @default.
• W2039455796 creator A5027204364 @default.
• W2039455796 creator A5043911586 @default.
• W2039455796 creator A5052453881 @default.
• W2039455796 date "1983-05-01" @default.
• W2039455796 modified "2023-10-15" @default.
• W2039455796 title "Regulation of rat urinary and renal kallikrein and prekallikrein by corticosteroids." @default.
• W2039455796 cites W1628920174 @default.
• W2039455796 cites W1775749144 @default.
• W2039455796 cites W1910458885 @default.
• W2039455796 cites W1998014245 @default.
• W2039455796 cites W2012375901 @default.
• W2039455796 cites W2014883831 @default.
• W2039455796 cites W2037200941 @default.
• W2039455796 cites W2043579594 @default.
• W2039455796 cites W2067620875 @default.
• W2039455796 cites W2068857576 @default.
• W2039455796 cites W2080941550 @default.
• W2039455796 cites W2098134973 @default.
• W2039455796 cites W2101134701 @default.
• W2039455796 cites W2101303350 @default.
• W2039455796 cites W2137069941 @default.
• W2039455796 cites W2146980048 @default.
• W2039455796 cites W2173637965 @default.
• W2039455796 cites W2232490291 @default.
• W2039455796 cites W2306599728 @default.
• W2039455796 cites W2319276474 @default.
• W2039455796 cites W2403149505 @default.
• W2039455796 cites W2411332483 @default.
• W2039455796 cites W2411362997 @default.
• W2039455796 cites W2416271724 @default.
• W2039455796 cites W2431349502 @default.
• W2039455796 cites W2472755452 @default.
• W2039455796 doi "https://doi.org/10.1073/pnas.80.10.3059" @default.
• W2039455796 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/393973" @default.
• W2039455796 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6344076" @default.
• W2039455796 hasPublicationYear "1983" @default.
• W2039455796 type Work @default.
• W2039455796 sameAs 2039455796 @default.
• W2039455796 citedByCount "27" @default.
• W2039455796 countsByYear W20394557962020 @default.
• W2039455796 crossrefType "journal-article" @default.
• W2039455796 hasAuthorship W2039455796A5011486327 @default.
• W2039455796 hasAuthorship W2039455796A5027204364 @default.
• W2039455796 hasAuthorship W2039455796A5043911586 @default.
• W2039455796 hasAuthorship W2039455796A5052453881 @default.
• W2039455796 hasBestOaLocation W20394557962 @default.
• W2039455796 hasConcept C10146269 @default.
• W2039455796 hasConcept C126322002 @default.
• W2039455796 hasConcept C134018914 @default.
• W2039455796 hasConcept C152328610 @default.
• W2039455796 hasConcept C170493617 @default.
• W2039455796 hasConcept C181199279 @default.
• W2039455796 hasConcept C185592680 @default.
• W2039455796 hasConcept C2776246183 @default.
• W2039455796 hasConcept C2779591629 @default.
• W2039455796 hasConcept C2780087391 @default.
• W2039455796 hasConcept C52853521 @default.
• W2039455796 hasConcept C55493867 @default.
• W2039455796 hasConcept C71924100 @default.
• W2039455796 hasConcept C86803240 @default.
• W2039455796 hasConceptScore W2039455796C10146269 @default.
• W2039455796 hasConceptScore W2039455796C126322002 @default.
• W2039455796 hasConceptScore W2039455796C134018914 @default.
• W2039455796 hasConceptScore W2039455796C152328610 @default.
• W2039455796 hasConceptScore W2039455796C170493617 @default.
• W2039455796 hasConceptScore W2039455796C181199279 @default.
• W2039455796 hasConceptScore W2039455796C185592680 @default.
• W2039455796 hasConceptScore W2039455796C2776246183 @default.
• W2039455796 hasConceptScore W2039455796C2779591629 @default.
• W2039455796 hasConceptScore W2039455796C2780087391 @default.
• W2039455796 hasConceptScore W2039455796C52853521 @default.
• W2039455796 hasConceptScore W2039455796C55493867 @default.
• W2039455796 hasConceptScore W2039455796C71924100 @default.
• W2039455796 hasConceptScore W2039455796C86803240 @default.
• W2039455796 hasIssue "10" @default.
• W2039455796 hasLocation W20394557961 @default.
• W2039455796 hasLocation W20394557962 @default.
• W2039455796 hasLocation W20394557963 @default.
• W2039455796 hasLocation W20394557964 @default.
• W2039455796 hasOpenAccess W2039455796 @default.
• W2039455796 hasPrimaryLocation W20394557961 @default.
• W2039455796 hasRelatedWork W112050163 @default.
• W2039455796 hasRelatedWork W1436712773 @default.
• W2039455796 hasRelatedWork W1873512938 @default.
• W2039455796 hasRelatedWork W1963666718 @default.
• W2039455796 hasRelatedWork W1982170684 @default.
• W2039455796 hasRelatedWork W199796774 @default.
• W2039455796 hasRelatedWork W2061552099 @default.
• W2039455796 hasRelatedWork W2071937323 @default.
• W2039455796 hasRelatedWork W2076131941 @default.
• W2039455796 hasRelatedWork W2474818678 @default.
• W2039455796 hasVolume "80" @default.
• W2039455796 isParatext "false" @default.
• W2039455796 isRetracted "false" @default.
• W2039455796 magId "2039455796" @default.

• next