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- W2039468245 abstract "Cationic yet natural oligonucleotides. A one-day automated synthesis of any oligonucleotide–oligospermine sequence was developed. Due to charge reversal, these compounds show increased duplex stability with their complementary sequence and are capable of performing strand replacement within a target duplex sequence. Due to a natural nucleic acid backbone, base-pair mismatch discrimination is retained. Diblock cationic oligonucleotides could find applications in diagnostics and therapy. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2268/2006/z600178_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article." @default.
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- W2039468245 date "2006-07-27" @default.
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- W2039468245 title "Online Synthesis of Diblock Cationic Oligonucleotides for Enhanced Hybridization to their Complementary Sequence" @default.
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- W2039468245 doi "https://doi.org/10.1002/cbic.200600178" @default.
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