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- W2039470968 abstract "Abstract We report a case of an 18‐month‐old boy with slightly whitened fingernails and toenails since birth. At the age of 100 days, he progressively developed bilateral palmoplantar keratoderma which resulted in painful walking and disabled grasping. Perianal keratotic plaques and perioral hyperkeratotic erythema could also be observed. Both fingernails and toenails were dystrophic. Scalp hairs were sparse, but total alopecia was no present. The histopathologic changes of the biopsy from the inner side of the right foot showed nonspecific changes, which mainly showed highly hyperkeratosis and acanthosis with slight superficial perivascular inflammatory infiltration. A clinical diagnosis of Olmsted syndrome was established according to the typical feature of the lesions, which is the presence of symmetrical palmoplantar keratoderma with periorificial keratotic plaques. We review the literature and present a summary of all reported cases to date." @default.
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- W2039470968 date "2008-04-14" @default.
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- W2039470968 title "Olmsted syndrome: a case report and review of literature" @default.
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- W2039470968 doi "https://doi.org/10.1111/j.1365-4632.2008.03595.x" @default.
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