FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039481232> ?p ?o ?g. }

• W2039481232 abstract "ATP-binding cassette (ABC) transporters represent an important family of membrane proteins involved in drug resistance and other biological activities. The present study reports on the characterization of a P-glycoprotein (Pgp), TgABC.B1, in the protozoan parasite Toxoplasma gondii. The protein encoded by the TgABC.B1 gene displays the typical (TMD-NBD)2 structural organization of the full ABC transporter and shows significant identity and similarity with two apicomplexan Pgps; Pgh1 in Plasmodium falciparum and CpABC3 in Cryptosporidium parvum. The TgABC.B1 gene is a single copy gene transcribed into a full-length mRNA of 4.3kb and expressed as a protein of approximately 150kDa, which cellular localization revealed a membrane-associated labelling in tachyzoites. The TgABC.B1 gene is constitutively expressed in the three major T. gondii genotypes but demonstrated a higher expression in virulent type I, at both transcriptional and translational levels. Further characterization of this Pgp-like protein will increase our knowledge of the membrane transport system in this parasite and could result in the identification of a new therapeutic target in Toxoplasma." @default.
• W2039481232 created "2016-06-24" @default.
• W2039481232 creator A5020886199 @default.
• W2039481232 creator A5046685692 @default.
• W2039481232 creator A5046794685 @default.
• W2039481232 creator A5051091895 @default.
• W2039481232 creator A5053581718 @default.
• W2039481232 creator A5060977861 @default.
• W2039481232 creator A5081889127 @default.
• W2039481232 date "2009-01-01" @default.
• W2039481232 modified "2023-10-05" @default.
• W2039481232 title "Molecular characterization and expression analysis of a P-glycoprotein homologue in Toxoplasma gondii" @default.
• W2039481232 cites W124504601 @default.
• W2039481232 cites W142952288 @default.
• W2039481232 cites W1957217069 @default.
• W2039481232 cites W1970621990 @default.
• W2039481232 cites W1994712912 @default.
• W2039481232 cites W2006332906 @default.
• W2039481232 cites W2009979935 @default.
• W2039481232 cites W2016102145 @default.
• W2039481232 cites W2028533496 @default.
• W2039481232 cites W2047623829 @default.
• W2039481232 cites W2048946490 @default.
• W2039481232 cites W2062068344 @default.
• W2039481232 cites W2068204754 @default.
• W2039481232 cites W2083522771 @default.
• W2039481232 cites W2090085993 @default.
• W2039481232 cites W2095518518 @default.
• W2039481232 cites W2101382252 @default.
• W2039481232 cites W2105214449 @default.
• W2039481232 cites W2151394787 @default.
• W2039481232 cites W2160778580 @default.
• W2039481232 cites W2162097287 @default.
• W2039481232 cites W2162958593 @default.
• W2039481232 cites W2166628294 @default.
• W2039481232 cites W3025190738 @default.
• W2039481232 doi "https://doi.org/10.1016/j.molbiopara.2008.09.010" @default.
• W2039481232 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18984013" @default.
• W2039481232 hasPublicationYear "2009" @default.
• W2039481232 type Work @default.
• W2039481232 sameAs 2039481232 @default.
• W2039481232 citedByCount "8" @default.
• W2039481232 countsByYear W20394812322012 @default.
• W2039481232 countsByYear W20394812322013 @default.
• W2039481232 countsByYear W20394812322014 @default.
• W2039481232 countsByYear W20394812322015 @default.
• W2039481232 countsByYear W20394812322017 @default.
• W2039481232 countsByYear W20394812322021 @default.
• W2039481232 crossrefType "journal-article" @default.
• W2039481232 hasAuthorship W2039481232A5020886199 @default.
• W2039481232 hasAuthorship W2039481232A5046685692 @default.
• W2039481232 hasAuthorship W2039481232A5046794685 @default.
• W2039481232 hasAuthorship W2039481232A5051091895 @default.
• W2039481232 hasAuthorship W2039481232A5053581718 @default.
• W2039481232 hasAuthorship W2039481232A5060977861 @default.
• W2039481232 hasAuthorship W2039481232A5081889127 @default.
• W2039481232 hasConcept C104317684 @default.
• W2039481232 hasConcept C108625454 @default.
• W2039481232 hasConcept C149011108 @default.
• W2039481232 hasConcept C150194340 @default.
• W2039481232 hasConcept C153911025 @default.
• W2039481232 hasConcept C159654299 @default.
• W2039481232 hasConcept C203014093 @default.
• W2039481232 hasConcept C2777795018 @default.
• W2039481232 hasConcept C2778048844 @default.
• W2039481232 hasConcept C2778128430 @default.
• W2039481232 hasConcept C2778371730 @default.
• W2039481232 hasConcept C2781023229 @default.
• W2039481232 hasConcept C44312359 @default.
• W2039481232 hasConcept C54355233 @default.
• W2039481232 hasConcept C60987743 @default.
• W2039481232 hasConcept C86803240 @default.
• W2039481232 hasConceptScore W2039481232C104317684 @default.
• W2039481232 hasConceptScore W2039481232C108625454 @default.
• W2039481232 hasConceptScore W2039481232C149011108 @default.
• W2039481232 hasConceptScore W2039481232C150194340 @default.
• W2039481232 hasConceptScore W2039481232C153911025 @default.
• W2039481232 hasConceptScore W2039481232C159654299 @default.
• W2039481232 hasConceptScore W2039481232C203014093 @default.
• W2039481232 hasConceptScore W2039481232C2777795018 @default.
• W2039481232 hasConceptScore W2039481232C2778048844 @default.
• W2039481232 hasConceptScore W2039481232C2778128430 @default.
• W2039481232 hasConceptScore W2039481232C2778371730 @default.
• W2039481232 hasConceptScore W2039481232C2781023229 @default.
• W2039481232 hasConceptScore W2039481232C44312359 @default.
• W2039481232 hasConceptScore W2039481232C54355233 @default.
• W2039481232 hasConceptScore W2039481232C60987743 @default.
• W2039481232 hasConceptScore W2039481232C86803240 @default.
• W2039481232 hasLocation W20394812321 @default.
• W2039481232 hasLocation W20394812322 @default.
• W2039481232 hasOpenAccess W2039481232 @default.
• W2039481232 hasPrimaryLocation W20394812321 @default.
• W2039481232 hasRelatedWork W1513988282 @default.
• W2039481232 hasRelatedWork W1976795005 @default.
• W2039481232 hasRelatedWork W2009966535 @default.
• W2039481232 hasRelatedWork W2039481232 @default.
• W2039481232 hasRelatedWork W2041559206 @default.
• W2039481232 hasRelatedWork W2050201605 @default.
• W2039481232 hasRelatedWork W2088063203 @default.
• W2039481232 hasRelatedWork W2091147248 @default.

• next