Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039485638> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2039485638 endingPage "4.6" @default.
- W2039485638 startingPage "4.1" @default.
- W2039485638 abstract "The most common type of microarray experiment has a simple design using microarray data obtained from two different groups or conditions. A typical method to identify differentially expressed genes (DEGs) between two conditions is the conventional Student`s t-test. The t-test is based on the simple estimation of the population variance for a gene using the sample variance of its expression levels. Although empirical Bayes approach improves on the t-statistic by not giving a high rank to genes only because they have a small sample variance, the basic assumption for this is same as the ordinary t-test which is the equality of variances across experimental groups. The t-test and empirical Bayes approach suffer from low statistical power because of the assumption of normal and unimodal distributions for the microarray data analysis. We propose a method to address these problems that is robust to outliers or skewed data, while maintaining the advantages of the classical t-test or modified t-statistics. The resulting data transformation to fit the normality assumption increases the statistical power for identifying DEGs using these statistics." @default.
- W2039485638 created "2016-06-24" @default.
- W2039485638 creator A5032931435 @default.
- W2039485638 creator A5054190886 @default.
- W2039485638 creator A5065515799 @default.
- W2039485638 creator A5083035763 @default.
- W2039485638 date "2010-06-30" @default.
- W2039485638 modified "2023-09-24" @default.
- W2039485638 title "Improved Statistical Testing of Two-class Microarrays with a Robust Statistical Approach" @default.
- W2039485638 cites W1970156673 @default.
- W2039485638 cites W1971289666 @default.
- W2039485638 cites W1985958957 @default.
- W2039485638 cites W2011696346 @default.
- W2039485638 cites W2021129827 @default.
- W2039485638 cites W2022345949 @default.
- W2039485638 cites W2048706383 @default.
- W2039485638 cites W2050567721 @default.
- W2039485638 cites W2054100651 @default.
- W2039485638 cites W2065742895 @default.
- W2039485638 cites W2074466695 @default.
- W2039485638 cites W2081098333 @default.
- W2039485638 cites W2110065044 @default.
- W2039485638 cites W2110891968 @default.
- W2039485638 cites W2115233298 @default.
- W2039485638 cites W2117711865 @default.
- W2039485638 cites W2136434805 @default.
- W2039485638 cites W2151566419 @default.
- W2039485638 cites W2157795344 @default.
- W2039485638 cites W2168578034 @default.
- W2039485638 cites W46151742 @default.
- W2039485638 doi "https://doi.org/10.4051/ibc.2010.2.2.0004" @default.
- W2039485638 hasPublicationYear "2010" @default.
- W2039485638 type Work @default.
- W2039485638 sameAs 2039485638 @default.
- W2039485638 citedByCount "0" @default.
- W2039485638 crossrefType "journal-article" @default.
- W2039485638 hasAuthorship W2039485638A5032931435 @default.
- W2039485638 hasAuthorship W2039485638A5054190886 @default.
- W2039485638 hasAuthorship W2039485638A5065515799 @default.
- W2039485638 hasAuthorship W2039485638A5083035763 @default.
- W2039485638 hasConcept C105795698 @default.
- W2039485638 hasConcept C114289077 @default.
- W2039485638 hasConcept C119857082 @default.
- W2039485638 hasConcept C124101348 @default.
- W2039485638 hasConcept C154945302 @default.
- W2039485638 hasConcept C2777212361 @default.
- W2039485638 hasConcept C2986587452 @default.
- W2039485638 hasConcept C33923547 @default.
- W2039485638 hasConcept C41008148 @default.
- W2039485638 hasConcept C87007009 @default.
- W2039485638 hasConceptScore W2039485638C105795698 @default.
- W2039485638 hasConceptScore W2039485638C114289077 @default.
- W2039485638 hasConceptScore W2039485638C119857082 @default.
- W2039485638 hasConceptScore W2039485638C124101348 @default.
- W2039485638 hasConceptScore W2039485638C154945302 @default.
- W2039485638 hasConceptScore W2039485638C2777212361 @default.
- W2039485638 hasConceptScore W2039485638C2986587452 @default.
- W2039485638 hasConceptScore W2039485638C33923547 @default.
- W2039485638 hasConceptScore W2039485638C41008148 @default.
- W2039485638 hasConceptScore W2039485638C87007009 @default.
- W2039485638 hasIssue "2" @default.
- W2039485638 hasLocation W20394856381 @default.
- W2039485638 hasOpenAccess W2039485638 @default.
- W2039485638 hasPrimaryLocation W20394856381 @default.
- W2039485638 hasRelatedWork W1971059585 @default.
- W2039485638 hasRelatedWork W2034883264 @default.
- W2039485638 hasRelatedWork W2086139622 @default.
- W2039485638 hasRelatedWork W2129097213 @default.
- W2039485638 hasRelatedWork W2147556030 @default.
- W2039485638 hasRelatedWork W2356483589 @default.
- W2039485638 hasRelatedWork W2359486277 @default.
- W2039485638 hasRelatedWork W2909645158 @default.
- W2039485638 hasRelatedWork W4321484743 @default.
- W2039485638 hasRelatedWork W755468467 @default.
- W2039485638 hasVolume "2" @default.
- W2039485638 isParatext "false" @default.
- W2039485638 isRetracted "false" @default.
- W2039485638 magId "2039485638" @default.
- W2039485638 workType "article" @default.