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- W2039506572 startingPage "3705" @default.
- W2039506572 abstract "The natural tripeptide antibiotic “Bialaphos” (5) has been synthesized by condensation of the protected L-phosphinothricin (1) with the dipeptide alanylalanine ethyl ester. The dicyclohexylcarbodiimide method has been used, followed by enzyme-catalyzed hydrolysis. Analogously, a cyclic analogue and the phosphac-peptide (phosphinic amide type) analogue (14) of the antibiotic (5) have been found to possess antitumour activity." @default.
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- W2039506572 date "1988-10-01" @default.
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- W2039506572 title "Organophosphorus Analogues and Derivatives of the Natural L-Amino Carboxylic Acids and Peptides. II. Synthesis, Enzyme-Substrate Interactions of “Bialaphos” (SF-1293) and Its Cyclic and Phosphinic Amide Type Analogues" @default.
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- W2039506572 doi "https://doi.org/10.1246/bcsj.61.3705" @default.
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