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- W2039531330 abstract "During the past decade there has been an extraordinary upsurge of clinical interest in arrhythmias, particularly those of ventricular origin. The potential risk for sudden death in certain situations complicated by arrhythmia is being increasingly recognized, and there is a continual search for suppressive therapy. TWO major developments, the establishment of the coronary care unit concept and the availability of pacemakers for both temporary and permanent use, have contributed to the physician’s current awareness of the potential significance of arrhythmias. Previously the clinician had no particular need for information available from the electrocardiographic or electrophysiologic laboratory-information that is now recognized to have important implications for health care. For example, electric defibrillation was studied by the French before the turn of this century1 and extensively evaluated by workers at Johns Hopkins in the 1920’s under the leadership of Kouwenhoven.2 This research was supported by the utilities because of concern about the hazard and treatment of high voltage electric shock. Wiggers3 suggested that electric shock administered directly to the heart might have important therapeutic uses. The techniques had limited application, however, until they were applied across the closed chest in the early 1950’s. Direct-current (d-c) shock was evaluated both by the Johns Hopkins group in the 1920’s and by the Russians during the 1940’s, but it was not until Lown et al.4 introduced the d-c defibrillator, less than 10 years ago, that the instrument became fashionable in this country. The concept of vulnerability was first demon-" @default.
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- W2039531330 date "1971-11-01" @default.
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- W2039531330 title "Arrhythmia, sudden death and coronary artery disease" @default.
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- W2039531330 doi "https://doi.org/10.1016/0002-9149(71)90106-8" @default.
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