Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039564969> ?p ?o ?g. }
- W2039564969 endingPage "248" @default.
- W2039564969 startingPage "233" @default.
- W2039564969 abstract "In S. cerevisiae, histone variant H2A.Z is deposited in euchromatin at the flanks of silent heterochromatin to prevent its ectopic spread. We show that H2A.Z nucleosomes are found at promoter regions of nearly all genes in euchromatin. They generally occur as two positioned nucleosomes that flank a nucleosome-free region (NFR) that contains the transcription start site. Astonishingly, enrichment at 5′ ends is observed not only at actively transcribed genes but also at inactive loci. Mutagenesis of a typical promoter revealed a 22 bp segment of DNA sufficient to program formation of a NFR flanked by two H2A.Z nucleosomes. This segment contains a binding site of the Myb-related protein Reb1 and an adjacent dT:dA tract. Efficient deposition of H2A.Z is further promoted by a specific pattern of histone H3 and H4 tail acetylation and the bromodomain protein Bdf1, a component of the Swr1 remodeling complex that deposits H2A.Z." @default.
- W2039564969 created "2016-06-24" @default.
- W2039564969 creator A5035618234 @default.
- W2039564969 creator A5039446566 @default.
- W2039564969 creator A5048199254 @default.
- W2039564969 creator A5051179946 @default.
- W2039564969 creator A5066554728 @default.
- W2039564969 creator A5074431279 @default.
- W2039564969 creator A5081945349 @default.
- W2039564969 creator A5083267835 @default.
- W2039564969 date "2005-10-01" @default.
- W2039564969 modified "2023-10-16" @default.
- W2039564969 title "Histone Variant H2A.Z Marks the 5′ Ends of Both Active and Inactive Genes in Euchromatin" @default.
- W2039564969 cites W1822988701 @default.
- W2039564969 cites W1846192773 @default.
- W2039564969 cites W1913652972 @default.
- W2039564969 cites W1966695495 @default.
- W2039564969 cites W1970970926 @default.
- W2039564969 cites W1972789688 @default.
- W2039564969 cites W1976172452 @default.
- W2039564969 cites W1989931191 @default.
- W2039564969 cites W1996270170 @default.
- W2039564969 cites W2006873092 @default.
- W2039564969 cites W2017261393 @default.
- W2039564969 cites W2029388127 @default.
- W2039564969 cites W2029734909 @default.
- W2039564969 cites W2033959188 @default.
- W2039564969 cites W2039940539 @default.
- W2039564969 cites W2042688172 @default.
- W2039564969 cites W2044681616 @default.
- W2039564969 cites W2050298575 @default.
- W2039564969 cites W2057332608 @default.
- W2039564969 cites W2058262378 @default.
- W2039564969 cites W2058368225 @default.
- W2039564969 cites W2058896391 @default.
- W2039564969 cites W2059698383 @default.
- W2039564969 cites W2061725821 @default.
- W2039564969 cites W2061867473 @default.
- W2039564969 cites W2069200751 @default.
- W2039564969 cites W2084509375 @default.
- W2039564969 cites W2087430129 @default.
- W2039564969 cites W2102155883 @default.
- W2039564969 cites W2103302926 @default.
- W2039564969 cites W2110312780 @default.
- W2039564969 cites W2113478190 @default.
- W2039564969 cites W2114803986 @default.
- W2039564969 cites W2121864789 @default.
- W2039564969 cites W2127481152 @default.
- W2039564969 cites W2132582704 @default.
- W2039564969 cites W2135951244 @default.
- W2039564969 cites W2137001129 @default.
- W2039564969 cites W2154708203 @default.
- W2039564969 cites W2161827767 @default.
- W2039564969 cites W2161880719 @default.
- W2039564969 cites W2162165765 @default.
- W2039564969 cites W2162865374 @default.
- W2039564969 cites W2163585426 @default.
- W2039564969 doi "https://doi.org/10.1016/j.cell.2005.10.002" @default.
- W2039564969 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2039754" @default.
- W2039564969 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16239142" @default.
- W2039564969 hasPublicationYear "2005" @default.
- W2039564969 type Work @default.
- W2039564969 sameAs 2039564969 @default.
- W2039564969 citedByCount "614" @default.
- W2039564969 countsByYear W20395649692012 @default.
- W2039564969 countsByYear W20395649692013 @default.
- W2039564969 countsByYear W20395649692014 @default.
- W2039564969 countsByYear W20395649692015 @default.
- W2039564969 countsByYear W20395649692016 @default.
- W2039564969 countsByYear W20395649692017 @default.
- W2039564969 countsByYear W20395649692018 @default.
- W2039564969 countsByYear W20395649692019 @default.
- W2039564969 countsByYear W20395649692020 @default.
- W2039564969 countsByYear W20395649692021 @default.
- W2039564969 countsByYear W20395649692022 @default.
- W2039564969 countsByYear W20395649692023 @default.
- W2039564969 crossrefType "journal-article" @default.
- W2039564969 hasAuthorship W2039564969A5035618234 @default.
- W2039564969 hasAuthorship W2039564969A5039446566 @default.
- W2039564969 hasAuthorship W2039564969A5048199254 @default.
- W2039564969 hasAuthorship W2039564969A5051179946 @default.
- W2039564969 hasAuthorship W2039564969A5066554728 @default.
- W2039564969 hasAuthorship W2039564969A5074431279 @default.
- W2039564969 hasAuthorship W2039564969A5081945349 @default.
- W2039564969 hasAuthorship W2039564969A5083267835 @default.
- W2039564969 hasBestOaLocation W20395649691 @default.
- W2039564969 hasConcept C10058791 @default.
- W2039564969 hasConcept C100924687 @default.
- W2039564969 hasConcept C103435993 @default.
- W2039564969 hasConcept C104317684 @default.
- W2039564969 hasConcept C150194340 @default.
- W2039564969 hasConcept C153911025 @default.
- W2039564969 hasConcept C173681060 @default.
- W2039564969 hasConcept C190727270 @default.
- W2039564969 hasConcept C22709980 @default.
- W2039564969 hasConcept C2779085176 @default.
- W2039564969 hasConcept C54355233 @default.
- W2039564969 hasConcept C56428682 @default.