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- W2039573693 abstract "A model for the shaping of cell sheets offers an interpretation for alternative structures which regenerate after a grafting operation. The model treats an epithelium as a thin shell which is fluid-like; cells in a small multicellular element can exchange neighbors to relieve shear stress. This fluidity allows interfacial tensions between groups of cells which differ in their adhesive affinities. The shell element bends elastically; its stiffness is associated with the cytoskeleton in each cell and with intercellular junctions. This fluid elastic shell model is used to model regeneration of the epithelium covering an insect or crustacean. The model suggests that mechanisms of regeneration minimize an energy functional. Typically regeneration restores the normal local pattern of structures everywhere in the epithelium. However, regenerated structures containing a few abnormal local patterns may also represent energy minima." @default.
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- W2039573693 date "1987-01-01" @default.
- W2039573693 modified "2023-09-26" @default.
- W2039573693 title "Triplication vs. duplication in regenerated arthropod limbs: multiple stable states in the shaping of cell sheets" @default.
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- W2039573693 doi "https://doi.org/10.1016/0270-0255(87)90645-2" @default.
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