FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039621761> ?p ?o ?g. }

• W2039621761 endingPage "704" @default.
• W2039621761 startingPage "699" @default.
• W2039621761 abstract "The effects of GABAB agonists and putative antagonists on intrasynaptosomal calcium ion concentrations ([Ca2+]i) after stimulation with potassium ions were studied with the fluorescent probe Quin 2. gamma-Aminobutyric acid and (-)-baclofen, but not (+)-baclofen, produced a dose-dependent inhibition of the potassium-stimulated [Ca2+]i in cortical synaptosomes from the rat. This effect was mimicked by another GABAB agonist SL75102 and weakly by muscimol. It was not inhibited by the alpha-adrenoceptor antagonist phentolamine. This system thus appears to provide a useful test of GABAB receptor function. None of the putative GABAB antagonists, phaclofen, delta-aminovaleric acid or beta-phenyl GABA inhibited responses to (-)-baclofen. Indeed, all three compounds produced similar responses to that seen with (-)-baclofen, suggesting that they act as agonists in this system. These data suggest that those GABAB receptors modulating [Ca2+]i have a distinct pharmacology from post-synaptic GABAB receptors, defined in electrophysiological experiments." @default.
• W2039621761 created "2016-06-24" @default.
• W2039621761 creator A5045731839 @default.
• W2039621761 creator A5056121164 @default.
• W2039621761 creator A5061917620 @default.
• W2039621761 creator A5072705376 @default.
• W2039621761 date "1989-07-01" @default.
• W2039621761 modified "2023-10-14" @default.
• W2039621761 title "The effects of GABAB receptor agonists and antagonists on potassium-stimulated [Ca2+]i in rat brain synaptosomes" @default.
• W2039621761 cites W1961539940 @default.
• W2039621761 cites W1964468967 @default.
• W2039621761 cites W1967284625 @default.
• W2039621761 cites W1987697310 @default.
• W2039621761 cites W1993303708 @default.
• W2039621761 cites W1993889485 @default.
• W2039621761 cites W1998407973 @default.
• W2039621761 cites W2016068732 @default.
• W2039621761 cites W2016609732 @default.
• W2039621761 cites W2020466006 @default.
• W2039621761 cites W2029863937 @default.
• W2039621761 cites W2031654230 @default.
• W2039621761 cites W2033976366 @default.
• W2039621761 cites W2036236793 @default.
• W2039621761 cites W2045085853 @default.
• W2039621761 cites W2049230063 @default.
• W2039621761 cites W2057433450 @default.
• W2039621761 cites W2070507880 @default.
• W2039621761 cites W2070558761 @default.
• W2039621761 cites W2075546028 @default.
• W2039621761 cites W2083954196 @default.
• W2039621761 cites W2090498959 @default.
• W2039621761 cites W2093347421 @default.
• W2039621761 cites W2165356988 @default.
• W2039621761 cites W2226364488 @default.
• W2039621761 cites W2237613670 @default.
• W2039621761 doi "https://doi.org/10.1016/0028-3908(89)90153-6" @default.
• W2039621761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2548111" @default.
• W2039621761 hasPublicationYear "1989" @default.
• W2039621761 type Work @default.
• W2039621761 sameAs 2039621761 @default.
• W2039621761 citedByCount "25" @default.
• W2039621761 countsByYear W20396217612014 @default.
• W2039621761 crossrefType "journal-article" @default.
• W2039621761 hasAuthorship W2039621761A5045731839 @default.
• W2039621761 hasAuthorship W2039621761A5056121164 @default.
• W2039621761 hasAuthorship W2039621761A5061917620 @default.
• W2039621761 hasAuthorship W2039621761A5072705376 @default.
• W2039621761 hasConcept C101027131 @default.
• W2039621761 hasConcept C126322002 @default.
• W2039621761 hasConcept C134018914 @default.
• W2039621761 hasConcept C168258287 @default.
• W2039621761 hasConcept C170493617 @default.
• W2039621761 hasConcept C178790620 @default.
• W2039621761 hasConcept C185592680 @default.
• W2039621761 hasConcept C24998067 @default.
• W2039621761 hasConcept C2776885963 @default.
• W2039621761 hasConcept C2778938600 @default.
• W2039621761 hasConcept C2780253649 @default.
• W2039621761 hasConcept C2781201050 @default.
• W2039621761 hasConcept C517785266 @default.
• W2039621761 hasConcept C55493867 @default.
• W2039621761 hasConcept C71924100 @default.
• W2039621761 hasConcept C86803240 @default.
• W2039621761 hasConcept C98274493 @default.
• W2039621761 hasConceptScore W2039621761C101027131 @default.
• W2039621761 hasConceptScore W2039621761C126322002 @default.
• W2039621761 hasConceptScore W2039621761C134018914 @default.
• W2039621761 hasConceptScore W2039621761C168258287 @default.
• W2039621761 hasConceptScore W2039621761C170493617 @default.
• W2039621761 hasConceptScore W2039621761C178790620 @default.
• W2039621761 hasConceptScore W2039621761C185592680 @default.
• W2039621761 hasConceptScore W2039621761C24998067 @default.
• W2039621761 hasConceptScore W2039621761C2776885963 @default.
• W2039621761 hasConceptScore W2039621761C2778938600 @default.
• W2039621761 hasConceptScore W2039621761C2780253649 @default.
• W2039621761 hasConceptScore W2039621761C2781201050 @default.
• W2039621761 hasConceptScore W2039621761C517785266 @default.
• W2039621761 hasConceptScore W2039621761C55493867 @default.
• W2039621761 hasConceptScore W2039621761C71924100 @default.
• W2039621761 hasConceptScore W2039621761C86803240 @default.
• W2039621761 hasConceptScore W2039621761C98274493 @default.
• W2039621761 hasIssue "7" @default.
• W2039621761 hasLocation W20396217611 @default.
• W2039621761 hasLocation W20396217612 @default.
• W2039621761 hasOpenAccess W2039621761 @default.
• W2039621761 hasPrimaryLocation W20396217611 @default.
• W2039621761 hasRelatedWork W1983696090 @default.
• W2039621761 hasRelatedWork W200825361 @default.
• W2039621761 hasRelatedWork W2030225289 @default.
• W2039621761 hasRelatedWork W2035291193 @default.
• W2039621761 hasRelatedWork W2038395458 @default.
• W2039621761 hasRelatedWork W2041646782 @default.
• W2039621761 hasRelatedWork W2056711535 @default.
• W2039621761 hasRelatedWork W2083079540 @default.
• W2039621761 hasRelatedWork W2099949194 @default.
• W2039621761 hasRelatedWork W2160740558 @default.
• W2039621761 hasVolume "28" @default.
• W2039621761 isParatext "false" @default.

• next