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- W2039622078 abstract "A top-down approach based on an emulsification–evaporation technique was used to prepare nanodispersions of astaxanthin. Response-surface methodology was employed to investigate the effect of the main processing conditions, namely, the applied pressure (20–90 MPa), number of cycles (0–4) and evaporation temperature (16–66 °C), on the average particle size, polydispersity index and astaxanthin concentration of the nanodispersions. Second-order polynomial regression models expressing the astaxanthin nanodispersion properties as functions of the main processing variables were significantly (p < 0.05) fitted, with high coefficient-of-determination values (R2 > 0.90). A multiple-optimisation procedure showed that the optimum conditions of pressure, number of cycles of homogenization and evaporation temperature, were 50 MPa, two cycles and 47 °C, respectively. A statistical assessment showed insignificant (p > 0.05) differences between experimental and predicted values, thus verifying the adequacy of the final reduced models fitted for explaining the variation of emulsion properties, as a function of homogenization and evaporation conditions." @default.
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- W2039622078 date "2010-11-01" @default.
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- W2039622078 title "Effect of processing conditions on physicochemical properties of astaxanthin nanodispersions" @default.
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- W2039622078 doi "https://doi.org/10.1016/j.foodchem.2010.05.036" @default.
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