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- W2039641280 abstract "The in vivo rates of protein synthesis in brains of control and methylmercury-treated rats were estimated by single injections of large quantities of low specific activity [U-14C]valine. The specific activities of free valine and protein-bound valine were determined to obtain the average rate of protein synthesis. The average rate in the cerebral cortex of the control rats was 0.75% replacement of protein-bound valine per hour. Methylmercury treatment decreased protein synthesis rates by 32% at the latent phase and by 15% at the symptomatic phase. In other brain regions studied, protein synthesis rates were also inhibited by methylmercury to various extent. The use of [U-14C]valine revealed that valine catabolism in the brain of control rats is different from that of methylmercury-treated animals." @default.
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- W2039641280 date "1980-11-01" @default.
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- W2039641280 title "Effect of methylmercury chloride on the in vivo rate of protein synthesis in the brain of the rat: Examination with the injection of a large quantity of 614C9valine" @default.
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- W2039641280 doi "https://doi.org/10.1016/0041-008x(80)90291-4" @default.
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