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• W2039651353 startingPage "224" @default.
• W2039651353 abstract "Previous research has reported a role for the neurotransmitter gamma-aminobutyric acid (GABA) in the extinction and renewal of conditioned fear. Here, the authors examine whether GABA is involved in the acquisition, extinction, renewal, spontaneous recovery, and latent inhibition of appetitive conditioning. Using Long-Evans rats, systemic injection of the GABA A receptor inverse agonist FG 7142 was shown to eliminate ABA renewal (Experiment 1) and spontaneous recovery (Experiment 4) of appetitive responding by selectively reducing the recovery of extinguished magazine approach. Furthermore, treatment with FG 7142 had no effects on acquisition or single-session extinction (Experiment 3) or on the context-specific expression of latent inhibition (Experiment 2). These data suggest that ABA renewal and spontaneous recovery, but not latent inhibition or responding during acquisition and an initial extinction session, are mediated by GABAergic mechanisms in appetitive Pavlovian conditioning. They provide support for the view that renewal and spontaneous recovery share a common psychological mechanism." @default.
• W2039651353 created "2016-06-24" @default.
• W2039651353 creator A5019014873 @default.
• W2039651353 creator A5041368993 @default.
• W2039651353 creator A5041741395 @default.
• W2039651353 date "2009-01-01" @default.
• W2039651353 modified "2023-09-27" @default.
• W2039651353 title "Renewal and spontaneous recovery, but not latent inhibition, are mediated by gamma-aminobutyric acid in appetitive conditioning." @default.
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• W2039651353 doi "https://doi.org/10.1037/a0013293" @default.
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