Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039658639> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2039658639 endingPage "2447" @default.
- W2039658639 startingPage "2439" @default.
- W2039658639 abstract "Background. To develop useful markers for the gastrointestinal neoplasms, the authors have established a new monoclonal antibody (MoAb), FU-MK-1, directed to gastric adenocarcinoma. Methods. The MoAb was produced by a mouse hybridoma technique by immunizing a BALB/c mouse with cancerous ascites derived from a poorly differentiated adenocarcinoma of the stomach. Results. FU-MK-1 did not react with the normal adult gastric mucosa, but did react with most carcinomas of the gastrointestinal tract. In addition, the MoAb recognized cholangiocarcinomas (CC), but it did not react with hepatocellular carcinomas (HCC). Furthermore, in the combined type tumor consisting of a mixture of HCC and CC, the MoAb react only with CC element, but not with pseudoglandular structures in the HCC areas. These results indicate that FU-MK-1 is a useful antigenic marker for distinguishing HCC from CC in the liver. Furthermore, because this MoAb retains its reactivity with formalin-fixed paraffin-embedded material, it may become a useful reagent for routine or retrospective immunohistologic studies. The molecular weight of the FU-MK-1 antigen was estimated to be ca. 41,000 dalton by the Western blot analysis. Periodic acid and trypsin treatment on the antigen suggested that the antigenic determinant is a glycoprotein. Conclusions. This MoAb may contribute to the histopathologic and immunologic studies of the digestive system." @default.
- W2039658639 created "2016-06-24" @default.
- W2039658639 creator A5020042735 @default.
- W2039658639 creator A5052168803 @default.
- W2039658639 creator A5062214131 @default.
- W2039658639 creator A5070398449 @default.
- W2039658639 creator A5078146302 @default.
- W2039658639 date "1993-04-15" @default.
- W2039658639 modified "2023-10-11" @default.
- W2039658639 title "A new tumor-associated antigen defined by a monoclonal antibody directed to gastric adenocarcinoma" @default.
- W2039658639 cites W1984108276 @default.
- W2039658639 cites W1988743038 @default.
- W2039658639 cites W2016076553 @default.
- W2039658639 cites W2018068034 @default.
- W2039658639 cites W2018846801 @default.
- W2039658639 cites W2022284603 @default.
- W2039658639 cites W2035014084 @default.
- W2039658639 cites W2036206708 @default.
- W2039658639 cites W2037680028 @default.
- W2039658639 cites W2038722446 @default.
- W2039658639 cites W2065500208 @default.
- W2039658639 cites W2067190395 @default.
- W2039658639 cites W2072910979 @default.
- W2039658639 cites W2098001605 @default.
- W2039658639 cites W2100837269 @default.
- W2039658639 cites W2116313133 @default.
- W2039658639 cites W2128898495 @default.
- W2039658639 cites W79637909 @default.
- W2039658639 doi "https://doi.org/10.1002/1097-0142(19930415)71:8<2439::aid-cncr2820710803>3.0.co;2-w" @default.
- W2039658639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7680948" @default.
- W2039658639 hasPublicationYear "1993" @default.
- W2039658639 type Work @default.
- W2039658639 sameAs 2039658639 @default.
- W2039658639 citedByCount "23" @default.
- W2039658639 countsByYear W20396586392013 @default.
- W2039658639 countsByYear W20396586392014 @default.
- W2039658639 crossrefType "journal-article" @default.
- W2039658639 hasAuthorship W2039658639A5020042735 @default.
- W2039658639 hasAuthorship W2039658639A5052168803 @default.
- W2039658639 hasAuthorship W2039658639A5062214131 @default.
- W2039658639 hasAuthorship W2039658639A5070398449 @default.
- W2039658639 hasAuthorship W2039658639A5078146302 @default.
- W2039658639 hasBestOaLocation W20396586391 @default.
- W2039658639 hasConcept C121608353 @default.
- W2039658639 hasConcept C126322002 @default.
- W2039658639 hasConcept C142724271 @default.
- W2039658639 hasConcept C147483822 @default.
- W2039658639 hasConcept C159654299 @default.
- W2039658639 hasConcept C163864487 @default.
- W2039658639 hasConcept C203014093 @default.
- W2039658639 hasConcept C204232928 @default.
- W2039658639 hasConcept C2779422922 @default.
- W2039658639 hasConcept C2780512811 @default.
- W2039658639 hasConcept C2781182431 @default.
- W2039658639 hasConcept C542903549 @default.
- W2039658639 hasConcept C71924100 @default.
- W2039658639 hasConcept C90924648 @default.
- W2039658639 hasConceptScore W2039658639C121608353 @default.
- W2039658639 hasConceptScore W2039658639C126322002 @default.
- W2039658639 hasConceptScore W2039658639C142724271 @default.
- W2039658639 hasConceptScore W2039658639C147483822 @default.
- W2039658639 hasConceptScore W2039658639C159654299 @default.
- W2039658639 hasConceptScore W2039658639C163864487 @default.
- W2039658639 hasConceptScore W2039658639C203014093 @default.
- W2039658639 hasConceptScore W2039658639C204232928 @default.
- W2039658639 hasConceptScore W2039658639C2779422922 @default.
- W2039658639 hasConceptScore W2039658639C2780512811 @default.
- W2039658639 hasConceptScore W2039658639C2781182431 @default.
- W2039658639 hasConceptScore W2039658639C542903549 @default.
- W2039658639 hasConceptScore W2039658639C71924100 @default.
- W2039658639 hasConceptScore W2039658639C90924648 @default.
- W2039658639 hasIssue "8" @default.
- W2039658639 hasLocation W20396586391 @default.
- W2039658639 hasLocation W20396586392 @default.
- W2039658639 hasOpenAccess W2039658639 @default.
- W2039658639 hasPrimaryLocation W20396586391 @default.
- W2039658639 hasRelatedWork W1966323553 @default.
- W2039658639 hasRelatedWork W1995553126 @default.
- W2039658639 hasRelatedWork W1999546986 @default.
- W2039658639 hasRelatedWork W2009919126 @default.
- W2039658639 hasRelatedWork W2129202804 @default.
- W2039658639 hasRelatedWork W2249843386 @default.
- W2039658639 hasRelatedWork W4231587522 @default.
- W2039658639 hasRelatedWork W4243269481 @default.
- W2039658639 hasRelatedWork W98141571 @default.
- W2039658639 hasRelatedWork W2064037489 @default.
- W2039658639 hasVolume "71" @default.
- W2039658639 isParatext "false" @default.
- W2039658639 isRetracted "false" @default.
- W2039658639 magId "2039658639" @default.
- W2039658639 workType "article" @default.