FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039683204> ?p ?o ?g. }

• W2039683204 endingPage "89" @default.
• W2039683204 startingPage "84" @default.
• W2039683204 abstract "Benzaldehyde lyase from Pseudomonas fluorescens (BAL, EC 4.1.2.38) is a versatile catalyst for stereoselective carboligations. Nevertheless, rather inconsistent data about its biochemical properties are reported in literature. In this study, the dependency of BAL activity on ionic strength, pH, and concentration of DMSO was for the first time systematically investigated and interpreted. It was found that the activity of BAL strongly depends on all three parameters, and a correlation exists between the dependency on pH and DMSO concentration. This correlation could be explained by an interaction of DMSO with an ionic amino acid in the catalytic site. A model-based analysis indicated that the pK(a) of this residue shifts to the alkaline milieu upon addition of DMSO. Consequently, the optimum pH also shifts to alkaline values when DMSO is present. Potentiometric experiments confirmed that the pK(a) can most probably be attributed to Glu50 which governs the activity increase of BAL on the acidic limb of its pH-activity profile. With these findings, the apparently contradicting data from literature become comprehensible and optimal reaction conditions for synthesis can easily be deduced." @default.
• W2039683204 created "2016-06-24" @default.
• W2039683204 creator A5009904674 @default.
• W2039683204 creator A5050242687 @default.
• W2039683204 creator A5062621205 @default.
• W2039683204 creator A5089252575 @default.
• W2039683204 date "2009-06-01" @default.
• W2039683204 modified "2023-10-04" @default.
• W2039683204 title "Biochemical peculiarities of benzaldehyde lyase from Pseudomonas fluorescens Biovar I in the dependency on pH and cosolvent concentration" @default.
• W2039683204 cites W1831794609 @default.
• W2039683204 cites W1913874700 @default.
• W2039683204 cites W1963881701 @default.
• W2039683204 cites W1983268283 @default.
• W2039683204 cites W1988395459 @default.
• W2039683204 cites W2028635434 @default.
• W2039683204 cites W2035651616 @default.
• W2039683204 cites W2046797984 @default.
• W2039683204 cites W2051528803 @default.
• W2039683204 cites W2055251598 @default.
• W2039683204 cites W2055394173 @default.
• W2039683204 cites W2075297931 @default.
• W2039683204 cites W2085157281 @default.
• W2039683204 cites W2086025910 @default.
• W2039683204 cites W2087314689 @default.
• W2039683204 cites W2091007335 @default.
• W2039683204 cites W2091761916 @default.
• W2039683204 cites W2092100607 @default.
• W2039683204 cites W2096964295 @default.
• W2039683204 cites W2105863191 @default.
• W2039683204 cites W2126381540 @default.
• W2039683204 cites W2136699027 @default.
• W2039683204 cites W2147038637 @default.
• W2039683204 cites W2155604981 @default.
• W2039683204 cites W2171830678 @default.
• W2039683204 cites W2949345715 @default.
• W2039683204 doi "https://doi.org/10.1016/j.bioorg.2009.03.001" @default.
• W2039683204 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19364619" @default.
• W2039683204 hasPublicationYear "2009" @default.
• W2039683204 type Work @default.
• W2039683204 sameAs 2039683204 @default.
• W2039683204 citedByCount "8" @default.
• W2039683204 countsByYear W20396832042012 @default.
• W2039683204 countsByYear W20396832042014 @default.
• W2039683204 countsByYear W20396832042018 @default.
• W2039683204 countsByYear W20396832042021 @default.
• W2039683204 crossrefType "journal-article" @default.
• W2039683204 hasAuthorship W2039683204A5009904674 @default.
• W2039683204 hasAuthorship W2039683204A5050242687 @default.
• W2039683204 hasAuthorship W2039683204A5062621205 @default.
• W2039683204 hasAuthorship W2039683204A5089252575 @default.
• W2039683204 hasConcept C124614425 @default.
• W2039683204 hasConcept C145148216 @default.
• W2039683204 hasConcept C161790260 @default.
• W2039683204 hasConcept C178790620 @default.
• W2039683204 hasConcept C179104552 @default.
• W2039683204 hasConcept C181199279 @default.
• W2039683204 hasConcept C184651966 @default.
• W2039683204 hasConcept C185592680 @default.
• W2039683204 hasConcept C187428577 @default.
• W2039683204 hasConcept C2182769 @default.
• W2039683204 hasConcept C2776835041 @default.
• W2039683204 hasConcept C2777269803 @default.
• W2039683204 hasConcept C2779692420 @default.
• W2039683204 hasConcept C523546767 @default.
• W2039683204 hasConcept C54355233 @default.
• W2039683204 hasConcept C71240020 @default.
• W2039683204 hasConcept C86803240 @default.
• W2039683204 hasConceptScore W2039683204C124614425 @default.
• W2039683204 hasConceptScore W2039683204C145148216 @default.
• W2039683204 hasConceptScore W2039683204C161790260 @default.
• W2039683204 hasConceptScore W2039683204C178790620 @default.
• W2039683204 hasConceptScore W2039683204C179104552 @default.
• W2039683204 hasConceptScore W2039683204C181199279 @default.
• W2039683204 hasConceptScore W2039683204C184651966 @default.
• W2039683204 hasConceptScore W2039683204C185592680 @default.
• W2039683204 hasConceptScore W2039683204C187428577 @default.
• W2039683204 hasConceptScore W2039683204C2182769 @default.
• W2039683204 hasConceptScore W2039683204C2776835041 @default.
• W2039683204 hasConceptScore W2039683204C2777269803 @default.
• W2039683204 hasConceptScore W2039683204C2779692420 @default.
• W2039683204 hasConceptScore W2039683204C523546767 @default.
• W2039683204 hasConceptScore W2039683204C54355233 @default.
• W2039683204 hasConceptScore W2039683204C71240020 @default.
• W2039683204 hasConceptScore W2039683204C86803240 @default.
• W2039683204 hasIssue "3" @default.
• W2039683204 hasLocation W20396832041 @default.
• W2039683204 hasLocation W20396832042 @default.
• W2039683204 hasOpenAccess W2039683204 @default.
• W2039683204 hasPrimaryLocation W20396832041 @default.
• W2039683204 hasRelatedWork W1966353166 @default.
• W2039683204 hasRelatedWork W1976834305 @default.
• W2039683204 hasRelatedWork W1987112035 @default.
• W2039683204 hasRelatedWork W1997650875 @default.
• W2039683204 hasRelatedWork W2008554258 @default.
• W2039683204 hasRelatedWork W2039683204 @default.
• W2039683204 hasRelatedWork W2068652451 @default.
• W2039683204 hasRelatedWork W2068776211 @default.
• W2039683204 hasRelatedWork W2801832594 @default.

• next