FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039701336> ?p ?o ?g. }

• W2039701336 endingPage "124" @default.
• W2039701336 startingPage "116" @default.
• W2039701336 abstract "This article reviews findings from longitudinal observational studies in both general and chronic obstructive pulmonary disease (COPD) populations, as well as from intervention trials in COPD, in which the annual rate of decline in forced expired volume in 1 s (FEV₁) has been measured. The purpose of the review is to describe the individual variability in rates of decline in FEV₁ within these populations, explore the factors contributing to this variability and discuss its implications.Individual rates of decline in FEV₁ have been found to vary considerably across participants with COPD in both observational cohorts and intervention trials from decreases as rapid as 150-200 ml per year to increases of up to approximately 150 ml per year, with mean rates of decline ranging from 33 to 69 ml per year. Aside from technical and biologic (e.g., time of day, season, weather, fatigue) sources of variation, other influential factors have included smoking status (most notably current versus former smoking), baseline smoking intensity, baseline lung function, airway hyperresponsiveness, exacerbation frequency, and, variably, age and sex. The presence of emphysema may also be a determinant, as well as certain biomarkers and gene variants.The wide distribution of individual rates of decline in FEV₁ includes especially rapid and slow declines. Future research is needed to identify biomarkers that both are predictive of a rapid decline within individuals who might then be targeted for special intervention and might also serve as surrogate endpoints in interventional trials." @default.
• W2039701336 created "2016-06-24" @default.
• W2039701336 creator A5062711392 @default.
• W2039701336 date "2013-03-01" @default.
• W2039701336 modified "2023-09-26" @default.
• W2039701336 title "Variations in FEV1 decline over time in chronic obstructive pulmonary disease and its implications" @default.
• W2039701336 cites W1859222707 @default.
• W2039701336 cites W1906550937 @default.
• W2039701336 cites W1920721512 @default.
• W2039701336 cites W1938844474 @default.
• W2039701336 cites W1977405309 @default.
• W2039701336 cites W1982193727 @default.
• W2039701336 cites W1999226863 @default.
• W2039701336 cites W2008414374 @default.
• W2039701336 cites W2017809609 @default.
• W2039701336 cites W2025782227 @default.
• W2039701336 cites W2031479986 @default.
• W2039701336 cites W203985185 @default.
• W2039701336 cites W2043657101 @default.
• W2039701336 cites W2045749557 @default.
• W2039701336 cites W2047546474 @default.
• W2039701336 cites W2048613195 @default.
• W2039701336 cites W2055820146 @default.
• W2039701336 cites W2063945782 @default.
• W2039701336 cites W2077279386 @default.
• W2039701336 cites W2085021685 @default.
• W2039701336 cites W2089124495 @default.
• W2039701336 cites W2096796935 @default.
• W2039701336 cites W2098643589 @default.
• W2039701336 cites W2103809903 @default.
• W2039701336 cites W2103823880 @default.
• W2039701336 cites W2105191262 @default.
• W2039701336 cites W2108665523 @default.
• W2039701336 cites W2110170053 @default.
• W2039701336 cites W2114656103 @default.
• W2039701336 cites W2122786331 @default.
• W2039701336 cites W2128010685 @default.
• W2039701336 cites W2132128923 @default.
• W2039701336 cites W2132565543 @default.
• W2039701336 cites W2133119676 @default.
• W2039701336 cites W2138808616 @default.
• W2039701336 cites W2140932829 @default.
• W2039701336 cites W2141034778 @default.
• W2039701336 cites W2162859596 @default.
• W2039701336 cites W2163229427 @default.
• W2039701336 cites W2164603088 @default.
• W2039701336 cites W2171676943 @default.
• W2039701336 cites W2268275976 @default.
• W2039701336 cites W2322866941 @default.
• W2039701336 cites W4320288047 @default.
• W2039701336 doi "https://doi.org/10.1097/mcp.0b013e32835d8ea4" @default.
• W2039701336 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23287286" @default.
• W2039701336 hasPublicationYear "2013" @default.
• W2039701336 type Work @default.
• W2039701336 sameAs 2039701336 @default.
• W2039701336 citedByCount "31" @default.
• W2039701336 countsByYear W20397013362013 @default.
• W2039701336 countsByYear W20397013362014 @default.
• W2039701336 countsByYear W20397013362015 @default.
• W2039701336 countsByYear W20397013362016 @default.
• W2039701336 countsByYear W20397013362017 @default.
• W2039701336 countsByYear W20397013362018 @default.
• W2039701336 countsByYear W20397013362019 @default.
• W2039701336 countsByYear W20397013362020 @default.
• W2039701336 countsByYear W20397013362021 @default.
• W2039701336 countsByYear W20397013362022 @default.
• W2039701336 crossrefType "journal-article" @default.
• W2039701336 hasAuthorship W2039701336A5062711392 @default.
• W2039701336 hasConcept C126322002 @default.
• W2039701336 hasConcept C144024400 @default.
• W2039701336 hasConcept C149923435 @default.
• W2039701336 hasConcept C168563851 @default.
• W2039701336 hasConcept C1862650 @default.
• W2039701336 hasConcept C23131810 @default.
• W2039701336 hasConcept C2776780178 @default.
• W2039701336 hasConcept C2777014857 @default.
• W2039701336 hasConcept C71924100 @default.
• W2039701336 hasConceptScore W2039701336C126322002 @default.
• W2039701336 hasConceptScore W2039701336C144024400 @default.
• W2039701336 hasConceptScore W2039701336C149923435 @default.
• W2039701336 hasConceptScore W2039701336C168563851 @default.
• W2039701336 hasConceptScore W2039701336C1862650 @default.
• W2039701336 hasConceptScore W2039701336C23131810 @default.
• W2039701336 hasConceptScore W2039701336C2776780178 @default.
• W2039701336 hasConceptScore W2039701336C2777014857 @default.
• W2039701336 hasConceptScore W2039701336C71924100 @default.
• W2039701336 hasIssue "2" @default.
• W2039701336 hasLocation W20397013361 @default.
• W2039701336 hasLocation W20397013362 @default.
• W2039701336 hasOpenAccess W2039701336 @default.
• W2039701336 hasPrimaryLocation W20397013361 @default.
• W2039701336 hasRelatedWork W1906133657 @default.
• W2039701336 hasRelatedWork W1974247132 @default.
• W2039701336 hasRelatedWork W2312821885 @default.
• W2039701336 hasRelatedWork W2777704906 @default.
• W2039701336 hasRelatedWork W2777951837 @default.
• W2039701336 hasRelatedWork W2898071577 @default.
• W2039701336 hasRelatedWork W3015451365 @default.

• next