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- W2039719972 abstract "Abstract 1.1. Pyribenzamine administered to dogs for a prolonged period (one year) in doses of 50 mg. to 100 mg. daily had no effect on the general behavior of the animals. 2.2. Furthermore, the drug did not produce a febrile reaction nor did it impair the kidney or liver function. Hematopoiesis was not altered in these animals. 3.3. Moreover, no chronic toxic changes were noted in the three human subjects who were given 150 mg. of pyribenzamine daily for eighty days. Such limited studies in man, however, are not sufficient as yet to attest to the complete harmlessness of the drug." @default.
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- W2039719972 date "1946-09-01" @default.
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- W2039719972 title "Chronic toxicity of N'pyridyl, N'benzyl, dimethyl-ethylenediamine monohydrochloride (pyribenzamine)" @default.
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- W2039719972 doi "https://doi.org/10.1016/0021-8707(46)90073-1" @default.
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