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- W2039729154 abstract "Hemorphins are endogenous opioids derived by enzymatic degradation of hemoglobin, a protein released in blood plasma during long distance running. We examined levels of β-endorphin and the heptapeptide hemorphin-7, in heparinized venous blood plasma from 15 sedentary controls (8 males, 7 females) and from 15 age- and sex-matched marathon runners at baseline and after running 42 km or 21 km. Baseline levels of β-endorphin (range 0.2–4.3 fmol/ml) were neither dependent upon weight, body mass index weight/height2, running status nor sex. Baseline levels of hemorphin-7 (range 0.2–6.9 pmol/ml) were lower in women (P<0.04) and covariated positively with body weight (P = 0.06), explaining lower levels in runners by their lower body weight. Covariation with body mass index was positive, but not significant (P = 0.10), however, here the dependence upon sex appeared stronger (P = 0.014). Running induced significant and correlated increases in hemorphin-7 and β-endorphin (r = 0.74; P<0.002), possibly indicating a functional relationship between these two peptides." @default.
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- W2039729154 date "1993-11-01" @default.
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- W2039729154 title "Concomitant increase in blood plasma levels of immunoreactive hemorphin-7 and β-endorphin following long distance running" @default.
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- W2039729154 doi "https://doi.org/10.1016/0167-0115(93)90378-l" @default.
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