Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039729233> ?p ?o ?g. }
- W2039729233 endingPage "1378" @default.
- W2039729233 startingPage "1371" @default.
- W2039729233 abstract "A functional immune system is important for the survival of mammalian young, particularly at weaning when they lose the immunological support provided by the mother's colostrum and milk. In altricial mammals, litter size and maternal characteristics are important components of an animal's early environment, which affect postnatal growth and development. In a study of unculled litters of Long-Evans laboratory rats (Rattus norvegicus), we asked whether such parameters are also associated with the immune status of the young shortly before weaning. On postnatal day 17, we assessed numbers of several leukocyte and lymphocyte subsets, the activity of the complement system, and immunoglobulin G (IgG) concentrations in the serum. Averaging the values of all pups per litter, we found negative correlations between litter size and lymphocyte counts, complement system activity and IgG concentration. Maternal effects were seen in the positive correlation between maternal postpartum body mass and granulocyte and monocyte counts. In addition, lymphocyte and monocyte counts as well as complement activity were lower for the young of multiparous than of primiparous mothers. This suggests a trend towards a better developed immune system in such offspring, which may be relevant for their immediate and long-term survival. The effects described here have potential implications for the design and interpretation of biomedical studies of immune parameters in laboratory rats." @default.
- W2039729233 created "2016-06-24" @default.
- W2039729233 creator A5006982475 @default.
- W2039729233 creator A5021869477 @default.
- W2039729233 creator A5062290816 @default.
- W2039729233 creator A5069680452 @default.
- W2039729233 date "2010-11-01" @default.
- W2039729233 modified "2023-09-30" @default.
- W2039729233 title "Family matters: Maternal and litter-size effects on immune parameters in young laboratory rats" @default.
- W2039729233 cites W1635246077 @default.
- W2039729233 cites W1963940334 @default.
- W2039729233 cites W1974012071 @default.
- W2039729233 cites W1979921649 @default.
- W2039729233 cites W1985088029 @default.
- W2039729233 cites W1990463170 @default.
- W2039729233 cites W1993551848 @default.
- W2039729233 cites W1999146924 @default.
- W2039729233 cites W1999354901 @default.
- W2039729233 cites W2001396193 @default.
- W2039729233 cites W2002439310 @default.
- W2039729233 cites W2004228142 @default.
- W2039729233 cites W2011353443 @default.
- W2039729233 cites W2020685059 @default.
- W2039729233 cites W2028334331 @default.
- W2039729233 cites W2029001547 @default.
- W2039729233 cites W2029186310 @default.
- W2039729233 cites W2033866128 @default.
- W2039729233 cites W2039984767 @default.
- W2039729233 cites W2044718585 @default.
- W2039729233 cites W2045573551 @default.
- W2039729233 cites W2046501432 @default.
- W2039729233 cites W2046788956 @default.
- W2039729233 cites W2047844446 @default.
- W2039729233 cites W2049079854 @default.
- W2039729233 cites W2050103719 @default.
- W2039729233 cites W2050308035 @default.
- W2039729233 cites W2050782363 @default.
- W2039729233 cites W2057010397 @default.
- W2039729233 cites W2058543617 @default.
- W2039729233 cites W2062483247 @default.
- W2039729233 cites W2062795275 @default.
- W2039729233 cites W2064501066 @default.
- W2039729233 cites W2065367502 @default.
- W2039729233 cites W2068602168 @default.
- W2039729233 cites W2069534775 @default.
- W2039729233 cites W2071265782 @default.
- W2039729233 cites W2073209502 @default.
- W2039729233 cites W2084508230 @default.
- W2039729233 cites W2091554355 @default.
- W2039729233 cites W2097285763 @default.
- W2039729233 cites W2100209152 @default.
- W2039729233 cites W2100309296 @default.
- W2039729233 cites W2105315723 @default.
- W2039729233 cites W2110374066 @default.
- W2039729233 cites W2114419044 @default.
- W2039729233 cites W2117089498 @default.
- W2039729233 cites W2123162799 @default.
- W2039729233 cites W2130133091 @default.
- W2039729233 cites W2134407629 @default.
- W2039729233 cites W2150216726 @default.
- W2039729233 cites W2152798205 @default.
- W2039729233 cites W2159228174 @default.
- W2039729233 cites W2159961413 @default.
- W2039729233 cites W2176090796 @default.
- W2039729233 cites W2315099521 @default.
- W2039729233 cites W2317475400 @default.
- W2039729233 cites W2323242806 @default.
- W2039729233 cites W4244695335 @default.
- W2039729233 cites W43565009 @default.
- W2039729233 doi "https://doi.org/10.1016/j.bbi.2010.07.240" @default.
- W2039729233 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20654710" @default.
- W2039729233 hasPublicationYear "2010" @default.
- W2039729233 type Work @default.
- W2039729233 sameAs 2039729233 @default.
- W2039729233 citedByCount "19" @default.
- W2039729233 countsByYear W20397292332012 @default.
- W2039729233 countsByYear W20397292332013 @default.
- W2039729233 countsByYear W20397292332014 @default.
- W2039729233 countsByYear W20397292332015 @default.
- W2039729233 countsByYear W20397292332016 @default.
- W2039729233 countsByYear W20397292332018 @default.
- W2039729233 countsByYear W20397292332020 @default.
- W2039729233 countsByYear W20397292332021 @default.
- W2039729233 countsByYear W20397292332022 @default.
- W2039729233 crossrefType "journal-article" @default.
- W2039729233 hasAuthorship W2039729233A5006982475 @default.
- W2039729233 hasAuthorship W2039729233A5021869477 @default.
- W2039729233 hasAuthorship W2039729233A5062290816 @default.
- W2039729233 hasAuthorship W2039729233A5069680452 @default.
- W2039729233 hasConcept C111850983 @default.
- W2039729233 hasConcept C112672928 @default.
- W2039729233 hasConcept C134018914 @default.
- W2039729233 hasConcept C159654299 @default.
- W2039729233 hasConcept C167654180 @default.
- W2039729233 hasConcept C18903297 @default.
- W2039729233 hasConcept C203014093 @default.
- W2039729233 hasConcept C2776659692 @default.
- W2039729233 hasConcept C2777761686 @default.