Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039738082> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2039738082 endingPage "465" @default.
- W2039738082 startingPage "451" @default.
- W2039738082 abstract "Abstract Beef brain tubulin isolated by cycles of polymerization and depolymerization contains two components, 6S subunit and a 25–35S boundary containing ring‐shaped aggregates of tubulin. The rings disappear during microtubule polymerization, and the incorporation of ring tubulin into microtubules has been investigated by studying the changes in the sedimentation of tubulin which occur during polymerization. The “30S” boundary was separated from the 6S boundary by sedimentation at low temperatures. The temperature was then raised by letting a small amount of air into the vacuum chamber and the changes in sedimentation rate and concentration of each component determined as the tubulin polymerized. The 30S material polymerizes preferentially as determined by its decrease in concentration at polymerizing temperatures. Simultaneously with its decrease in concentration the 30S also decreases in sedimentation rate. The decrease in concentration of the 30S correlates well with polymerization while the decrease in sedimentation rate can occur independently of polymerization. The results indicate that the rings are not transformed directly into microtubules, but break down into subunits or small aggregates and these then assemble into microtubules. The rings may serve as a “storage aggregate” of active subunits. The presence of a possible storage aggregate in a dividing cell, the eggs of the surf clam, Spisula solidissima, has been indicated by measurements of particulate tubulin changes during the cell cycle. Microtubule assembly in vitro in homogenates of these eggs indicates that the amount of tubulin which forms microtubules may be controlled by the functioning of the microtubule organizing center." @default.
- W2039738082 created "2016-06-24" @default.
- W2039738082 creator A5088672503 @default.
- W2039738082 date "1974-01-01" @default.
- W2039738082 modified "2023-10-03" @default.
- W2039738082 title "The role of ring aggregates and other structures in the assembly of microtubules" @default.
- W2039738082 cites W1976241888 @default.
- W2039738082 cites W1976576149 @default.
- W2039738082 cites W2014636427 @default.
- W2039738082 cites W2042212851 @default.
- W2039738082 cites W2044499660 @default.
- W2039738082 cites W2044966306 @default.
- W2039738082 cites W2444677183 @default.
- W2039738082 doi "https://doi.org/10.1002/jss.400020231" @default.
- W2039738082 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4437181" @default.
- W2039738082 hasPublicationYear "1974" @default.
- W2039738082 type Work @default.
- W2039738082 sameAs 2039738082 @default.
- W2039738082 citedByCount "43" @default.
- W2039738082 countsByYear W20397380822022 @default.
- W2039738082 crossrefType "journal-article" @default.
- W2039738082 hasAuthorship W2039738082A5088672503 @default.
- W2039738082 hasBestOaLocation W20397380821 @default.
- W2039738082 hasConcept C12554922 @default.
- W2039738082 hasConcept C1388644 @default.
- W2039738082 hasConcept C151730666 @default.
- W2039738082 hasConcept C178790620 @default.
- W2039738082 hasConcept C181199279 @default.
- W2039738082 hasConcept C185592680 @default.
- W2039738082 hasConcept C188027245 @default.
- W2039738082 hasConcept C20418707 @default.
- W2039738082 hasConcept C2816523 @default.
- W2039738082 hasConcept C29941650 @default.
- W2039738082 hasConcept C44228677 @default.
- W2039738082 hasConcept C49852136 @default.
- W2039738082 hasConcept C521977710 @default.
- W2039738082 hasConcept C55493867 @default.
- W2039738082 hasConcept C84425145 @default.
- W2039738082 hasConcept C86803240 @default.
- W2039738082 hasConcept C95444343 @default.
- W2039738082 hasConceptScore W2039738082C12554922 @default.
- W2039738082 hasConceptScore W2039738082C1388644 @default.
- W2039738082 hasConceptScore W2039738082C151730666 @default.
- W2039738082 hasConceptScore W2039738082C178790620 @default.
- W2039738082 hasConceptScore W2039738082C181199279 @default.
- W2039738082 hasConceptScore W2039738082C185592680 @default.
- W2039738082 hasConceptScore W2039738082C188027245 @default.
- W2039738082 hasConceptScore W2039738082C20418707 @default.
- W2039738082 hasConceptScore W2039738082C2816523 @default.
- W2039738082 hasConceptScore W2039738082C29941650 @default.
- W2039738082 hasConceptScore W2039738082C44228677 @default.
- W2039738082 hasConceptScore W2039738082C49852136 @default.
- W2039738082 hasConceptScore W2039738082C521977710 @default.
- W2039738082 hasConceptScore W2039738082C55493867 @default.
- W2039738082 hasConceptScore W2039738082C84425145 @default.
- W2039738082 hasConceptScore W2039738082C86803240 @default.
- W2039738082 hasConceptScore W2039738082C95444343 @default.
- W2039738082 hasIssue "2-4" @default.
- W2039738082 hasLocation W20397380821 @default.
- W2039738082 hasLocation W20397380822 @default.
- W2039738082 hasOpenAccess W2039738082 @default.
- W2039738082 hasPrimaryLocation W20397380821 @default.
- W2039738082 hasRelatedWork W1555013184 @default.
- W2039738082 hasRelatedWork W1996673908 @default.
- W2039738082 hasRelatedWork W2011521398 @default.
- W2039738082 hasRelatedWork W2012200185 @default.
- W2039738082 hasRelatedWork W2039738082 @default.
- W2039738082 hasRelatedWork W2050993411 @default.
- W2039738082 hasRelatedWork W2065941352 @default.
- W2039738082 hasRelatedWork W2083178979 @default.
- W2039738082 hasRelatedWork W2114083778 @default.
- W2039738082 hasRelatedWork W2117934352 @default.
- W2039738082 hasVolume "2" @default.
- W2039738082 isParatext "false" @default.
- W2039738082 isRetracted "false" @default.
- W2039738082 magId "2039738082" @default.
- W2039738082 workType "article" @default.