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• W2039748492 abstract "Asthma is an obstructive pulmonary disorder with exacerbations characterized by symptoms of shortness of breath, cough, chest tightness, and/or wheezing . Symptoms are caused by chronic airway inflammation . There are multiple cell types and inflammatory mediators involved in its pathophysiology . The airway inflammation is frequently mediated by Th2 lymphocytes, whose cytokine secretion leads to mast cell stimulation, eosinophilia , leukocytosis , and enhanced B-cell IgE production. Although various genes have been identified as likely contributors to asthma development, asthma is largely environmentally triggered and has a multifactorial cause. Asthma is extremely common, especially in poor, urban environments. Asthma is the third most common reason for pediatric hospitalizations." @default.
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• W2039748492 date "2014-02-01" @default.
• W2039748492 modified "2023-09-25" @default.
• W2039748492 title "What is Asthma? Pathophysiology, Demographics, and Health Care Costs" @default.
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• W2039748492 doi "https://doi.org/10.1016/j.otc.2013.09.010" @default.
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