Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039774345> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2039774345 endingPage "372" @default.
- W2039774345 startingPage "361" @default.
- W2039774345 abstract "Carefully controlled allergen inhalation tests were carried out in twelve subjects to provoke early asthmatic responses with a mean maximum FEV1 fall of 30·7 ± 5·2% (mean ± s.d.). Four subjects had additional late asthmatic responses with a maximum mean FEV1 fall of 21·0 ± 5·9%. The tests were repeated at intervals of 7 days in an identical way, following inhalation of Sch1000 (80 μg) and placebo, each given 45 min before the onset of the early asthmatic response. This dose of Sch1000 produced a marked and uniform inhibition of methacholine-induced bronchoconstriction in the same subjects. The allergen-induced responses were reproducible in eleven out of the twelve subjects; the coefficient of variation for the decrease in FEV1 in the early responses being ±7% and in the late response ±43%. Sch1000 produced a slight and variable inhibition of early asthmatic responses (P<0·02) and no inhibition of late asthmatic responses. We examined the relationship between the degree of inhibition of the early asthmatic response by Sch1000 and: (a) the degree of inhibition produced by Sch1000 on histamine- and methacholine-induced bronchoconstriction; (b) the level of non-specific bronchial reactivity measured by inhaled histamine and methacholine; and (c) the degree of bronchodilatation produced by Sch1000. No relationship was found." @default.
- W2039774345 created "2016-06-24" @default.
- W2039774345 creator A5038536018 @default.
- W2039774345 creator A5042721578 @default.
- W2039774345 creator A5068367175 @default.
- W2039774345 date "1978-07-01" @default.
- W2039774345 modified "2023-09-28" @default.
- W2039774345 title "Effect of Sch1000 in allergen-induced asthma" @default.
- W2039774345 cites W2001728531 @default.
- W2039774345 cites W2002199871 @default.
- W2039774345 cites W2004419411 @default.
- W2039774345 cites W2008872290 @default.
- W2039774345 cites W2047163318 @default.
- W2039774345 cites W2056474311 @default.
- W2039774345 cites W2056824209 @default.
- W2039774345 cites W2068558412 @default.
- W2039774345 cites W2094331081 @default.
- W2039774345 cites W2099947428 @default.
- W2039774345 cites W2137401824 @default.
- W2039774345 cites W2178556043 @default.
- W2039774345 cites W2351197400 @default.
- W2039774345 cites W2411749446 @default.
- W2039774345 cites W4237954461 @default.
- W2039774345 doi "https://doi.org/10.1111/j.1365-2222.1978.tb00471.x" @default.
- W2039774345 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/152170" @default.
- W2039774345 hasPublicationYear "1978" @default.
- W2039774345 type Work @default.
- W2039774345 sameAs 2039774345 @default.
- W2039774345 citedByCount "38" @default.
- W2039774345 countsByYear W20397743452012 @default.
- W2039774345 countsByYear W20397743452013 @default.
- W2039774345 countsByYear W20397743452014 @default.
- W2039774345 countsByYear W20397743452022 @default.
- W2039774345 crossrefType "journal-article" @default.
- W2039774345 hasAuthorship W2039774345A5038536018 @default.
- W2039774345 hasAuthorship W2039774345A5042721578 @default.
- W2039774345 hasAuthorship W2039774345A5068367175 @default.
- W2039774345 hasConcept C110586980 @default.
- W2039774345 hasConcept C1122143 @default.
- W2039774345 hasConcept C126322002 @default.
- W2039774345 hasConcept C142724271 @default.
- W2039774345 hasConcept C203014093 @default.
- W2039774345 hasConcept C204787440 @default.
- W2039774345 hasConcept C207480886 @default.
- W2039774345 hasConcept C27081682 @default.
- W2039774345 hasConcept C2776042228 @default.
- W2039774345 hasConcept C2776178081 @default.
- W2039774345 hasConcept C2776371117 @default.
- W2039774345 hasConcept C2776954882 @default.
- W2039774345 hasConcept C2777714996 @default.
- W2039774345 hasConcept C2780510475 @default.
- W2039774345 hasConcept C2780769369 @default.
- W2039774345 hasConcept C2781018748 @default.
- W2039774345 hasConcept C2781260171 @default.
- W2039774345 hasConcept C42219234 @default.
- W2039774345 hasConcept C71924100 @default.
- W2039774345 hasConceptScore W2039774345C110586980 @default.
- W2039774345 hasConceptScore W2039774345C1122143 @default.
- W2039774345 hasConceptScore W2039774345C126322002 @default.
- W2039774345 hasConceptScore W2039774345C142724271 @default.
- W2039774345 hasConceptScore W2039774345C203014093 @default.
- W2039774345 hasConceptScore W2039774345C204787440 @default.
- W2039774345 hasConceptScore W2039774345C207480886 @default.
- W2039774345 hasConceptScore W2039774345C27081682 @default.
- W2039774345 hasConceptScore W2039774345C2776042228 @default.
- W2039774345 hasConceptScore W2039774345C2776178081 @default.
- W2039774345 hasConceptScore W2039774345C2776371117 @default.
- W2039774345 hasConceptScore W2039774345C2776954882 @default.
- W2039774345 hasConceptScore W2039774345C2777714996 @default.
- W2039774345 hasConceptScore W2039774345C2780510475 @default.
- W2039774345 hasConceptScore W2039774345C2780769369 @default.
- W2039774345 hasConceptScore W2039774345C2781018748 @default.
- W2039774345 hasConceptScore W2039774345C2781260171 @default.
- W2039774345 hasConceptScore W2039774345C42219234 @default.
- W2039774345 hasConceptScore W2039774345C71924100 @default.
- W2039774345 hasIssue "4" @default.
- W2039774345 hasLocation W20397743451 @default.
- W2039774345 hasLocation W20397743452 @default.
- W2039774345 hasOpenAccess W2039774345 @default.
- W2039774345 hasPrimaryLocation W20397743451 @default.
- W2039774345 hasRelatedWork W2014006113 @default.
- W2039774345 hasRelatedWork W2024804850 @default.
- W2039774345 hasRelatedWork W2032612816 @default.
- W2039774345 hasRelatedWork W2039774345 @default.
- W2039774345 hasRelatedWork W2062489210 @default.
- W2039774345 hasRelatedWork W2066635153 @default.
- W2039774345 hasRelatedWork W2102829216 @default.
- W2039774345 hasRelatedWork W2133504959 @default.
- W2039774345 hasRelatedWork W2133516569 @default.
- W2039774345 hasRelatedWork W2418805611 @default.
- W2039774345 hasVolume "8" @default.
- W2039774345 isParatext "false" @default.
- W2039774345 isRetracted "false" @default.
- W2039774345 magId "2039774345" @default.
- W2039774345 workType "article" @default.