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• W2039776863 abstract "Objective This study aims to determine whether vitamin D levels are associated with menopause-related symptoms in older women. Methods A randomly selected subset of 1,407 women, among 26,104 potentially eligible participants of the Women’s Health Initiative Calcium and Vitamin D trial of postmenopausal women aged 51 to 80 years, had 25-hydroxyvitamin D [25(OH)D] levels measured at the Women’s Health Initiative Calcium and Vitamin D trial baseline visit. Information about menopause-related symptoms at baseline was obtained by questionnaire and included overall number of symptoms and composite measures of sleep disturbance, emotional well-being, and energy/fatigue, as well as individual symptoms. After exclusions for missing data, 530 women (mean [SD] age, 66.2 [6.8] y) were included in these analyses. Results Borderline significant associations between 25(OH)D levels and total number of menopausal symptoms were observed (with P values ranging from 0.05 to 0.06 for fully adjusted models); however, the effect was clinically insignificant and disappeared with correction for multiple testing. No associations between 25(OH)D levels and composite measures of sleep disturbance, emotional well-being, or energy/fatigue were observed (P’s > 0.10 for fully adjusted models). Conclusions There is no evidence for a clinically important association between serum 25(OH)D levels and menopause-related symptoms in postmenopausal women." @default.
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• W2039776863 date "2014-11-01" @default.
• W2039776863 modified "2023-10-18" @default.
• W2039776863 title "Vitamin D levels and menopause-related symptoms" @default.
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• W2039776863 doi "https://doi.org/10.1097/gme.0000000000000238" @default.
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