Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039779757> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2039779757 endingPage "1059" @default.
- W2039779757 startingPage "1053" @default.
- W2039779757 abstract "Deficient or toxic levels of selenium (Se) are known to impair immune function. Peripheral blood mononuclear cells (PBMC) were isolated from Holstein heifers of adequate Se status. PBMC were plated at densities of 0.5, 1.0, and 2.0 × 105 cells/well in 96-well microtiter plates and stimulated with T-cell mitogens, concanavalin A (ConA) and phytohemagglutinin-P (PHAP), and pokeweed mitogen (PWM), a T-dependent B-cell mitogen. Sera incorporated into the incubation system were from two newborn calves born to Se-deficient dams and averaged 20 ng Se/ml. Se additions of 50-400 ng/ml resulted in significant enhancement of PWM-stimulated proliferation relative to controls (no added Se). Enhancement of proliferation was cell density dependent, occurring predominately at a density of 0.5 × 105 cells/well. In contrast, proliferative responses of PBMC to ConA and PHAP were generally not enhanced by repletion with the lower levels of Se. Supplementation with higher levels of Se (1600–3200 ng/ml) inhibited proliferative responses to all mitogens tested regardless of cell density in culture. In summary, repletion with physiological levels of Se selectively stimulated B-cell proliferation an effect which was dependent on cell density." @default.
- W2039779757 created "2016-06-24" @default.
- W2039779757 creator A5023408977 @default.
- W2039779757 creator A5059460889 @default.
- W2039779757 creator A5062843024 @default.
- W2039779757 date "1990-09-01" @default.
- W2039779757 modified "2023-09-27" @default.
- W2039779757 title "Effect of in vitro selenium repletion on bovine lymphocyte proliferation" @default.
- W2039779757 cites W1962264982 @default.
- W2039779757 cites W1964685542 @default.
- W2039779757 cites W1976733277 @default.
- W2039779757 cites W2056377342 @default.
- W2039779757 cites W2069520931 @default.
- W2039779757 cites W2081032654 @default.
- W2039779757 cites W2093093145 @default.
- W2039779757 cites W2188569110 @default.
- W2039779757 cites W2339980039 @default.
- W2039779757 doi "https://doi.org/10.1016/s0271-5317(05)80047-8" @default.
- W2039779757 hasPublicationYear "1990" @default.
- W2039779757 type Work @default.
- W2039779757 sameAs 2039779757 @default.
- W2039779757 citedByCount "14" @default.
- W2039779757 countsByYear W20397797572017 @default.
- W2039779757 countsByYear W20397797572019 @default.
- W2039779757 countsByYear W20397797572020 @default.
- W2039779757 countsByYear W20397797572022 @default.
- W2039779757 crossrefType "journal-article" @default.
- W2039779757 hasAuthorship W2039779757A5023408977 @default.
- W2039779757 hasAuthorship W2039779757A5059460889 @default.
- W2039779757 hasAuthorship W2039779757A5062843024 @default.
- W2039779757 hasConcept C126322002 @default.
- W2039779757 hasConcept C134018914 @default.
- W2039779757 hasConcept C137061746 @default.
- W2039779757 hasConcept C153911025 @default.
- W2039779757 hasConcept C19869320 @default.
- W2039779757 hasConcept C202751555 @default.
- W2039779757 hasConcept C203014093 @default.
- W2039779757 hasConcept C2777761686 @default.
- W2039779757 hasConcept C2781005381 @default.
- W2039779757 hasConcept C55493867 @default.
- W2039779757 hasConcept C62112901 @default.
- W2039779757 hasConcept C71924100 @default.
- W2039779757 hasConcept C86803240 @default.
- W2039779757 hasConcept C8891405 @default.
- W2039779757 hasConceptScore W2039779757C126322002 @default.
- W2039779757 hasConceptScore W2039779757C134018914 @default.
- W2039779757 hasConceptScore W2039779757C137061746 @default.
- W2039779757 hasConceptScore W2039779757C153911025 @default.
- W2039779757 hasConceptScore W2039779757C19869320 @default.
- W2039779757 hasConceptScore W2039779757C202751555 @default.
- W2039779757 hasConceptScore W2039779757C203014093 @default.
- W2039779757 hasConceptScore W2039779757C2777761686 @default.
- W2039779757 hasConceptScore W2039779757C2781005381 @default.
- W2039779757 hasConceptScore W2039779757C55493867 @default.
- W2039779757 hasConceptScore W2039779757C62112901 @default.
- W2039779757 hasConceptScore W2039779757C71924100 @default.
- W2039779757 hasConceptScore W2039779757C86803240 @default.
- W2039779757 hasConceptScore W2039779757C8891405 @default.
- W2039779757 hasIssue "9" @default.
- W2039779757 hasLocation W20397797571 @default.
- W2039779757 hasOpenAccess W2039779757 @default.
- W2039779757 hasPrimaryLocation W20397797571 @default.
- W2039779757 hasRelatedWork W1988511806 @default.
- W2039779757 hasRelatedWork W1997681068 @default.
- W2039779757 hasRelatedWork W2039779757 @default.
- W2039779757 hasRelatedWork W2102735981 @default.
- W2039779757 hasRelatedWork W2130964140 @default.
- W2039779757 hasRelatedWork W2151014874 @default.
- W2039779757 hasRelatedWork W2193990762 @default.
- W2039779757 hasRelatedWork W2327157030 @default.
- W2039779757 hasRelatedWork W2418580515 @default.
- W2039779757 hasRelatedWork W306624267 @default.
- W2039779757 hasVolume "10" @default.
- W2039779757 isParatext "false" @default.
- W2039779757 isRetracted "false" @default.
- W2039779757 magId "2039779757" @default.
- W2039779757 workType "article" @default.