Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039836948> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2039836948 endingPage "330" @default.
- W2039836948 startingPage "329" @default.
- W2039836948 abstract "Four out of six long-term murine cytotoxic T lymphocyte (CTL) clones specific for trinitrophenyl (TNP)-modified spleen cells could develop an anomalous cytotoxicity against syngeneic and allogeneic tumor cells upon stimulation with TNP-modified spleen cells and high doses of human recombinant interleukin 2 (rIL-2). On FACS analysis, hyperactivated CTLs were positive for Thy-1, Ly 2 and LFA-1, but negative for L3T4 and asialo GM1. The staining profile of the cells with each antibody indicated that the CTL clones consisted of just one cell type. Monoclonal anti-Ly 2.2 and anti-LAA (lymphokine-activated cell-associated antigen) antibodies inhibited cytolysis of CTL and hyperactivated CTL clones against TNP-modified spleen cells, but failed to inhibit the anomalous killing of the hyperactivated CTL. The cold target competition test suggested the degeneracy of antigen specificity. The present study demonstrated that the CTL clone acquired a new specificity for tumor target cells upon stimulation with a high dose of rIL-2." @default.
- W2039836948 created "2016-06-24" @default.
- W2039836948 creator A5003868871 @default.
- W2039836948 creator A5022725690 @default.
- W2039836948 date "1982-12-01" @default.
- W2039836948 modified "2023-09-23" @default.
- W2039836948 title "The construction and immunocompetence of totally allogeneic mouse radiation chimeras" @default.
- W2039836948 cites W1535493568 @default.
- W2039836948 cites W1592685297 @default.
- W2039836948 cites W1596182019 @default.
- W2039836948 cites W1967392917 @default.
- W2039836948 cites W1971826113 @default.
- W2039836948 cites W2019341074 @default.
- W2039836948 cites W2038514094 @default.
- W2039836948 cites W2057350560 @default.
- W2039836948 cites W2073478494 @default.
- W2039836948 cites W2078091891 @default.
- W2039836948 cites W2138255951 @default.
- W2039836948 doi "https://doi.org/10.1016/0167-5699(82)90016-0" @default.
- W2039836948 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25290674" @default.
- W2039836948 hasPublicationYear "1982" @default.
- W2039836948 type Work @default.
- W2039836948 sameAs 2039836948 @default.
- W2039836948 citedByCount "0" @default.
- W2039836948 crossrefType "journal-article" @default.
- W2039836948 hasAuthorship W2039836948A5003868871 @default.
- W2039836948 hasAuthorship W2039836948A5022725690 @default.
- W2039836948 hasConcept C147483822 @default.
- W2039836948 hasConcept C147969180 @default.
- W2039836948 hasConcept C153911025 @default.
- W2039836948 hasConcept C154317977 @default.
- W2039836948 hasConcept C159047783 @default.
- W2039836948 hasConcept C159654299 @default.
- W2039836948 hasConcept C167672396 @default.
- W2039836948 hasConcept C202751555 @default.
- W2039836948 hasConcept C203014093 @default.
- W2039836948 hasConcept C2777371288 @default.
- W2039836948 hasConcept C2780931953 @default.
- W2039836948 hasConcept C2992881475 @default.
- W2039836948 hasConcept C49382859 @default.
- W2039836948 hasConcept C542903549 @default.
- W2039836948 hasConcept C54355233 @default.
- W2039836948 hasConcept C552990157 @default.
- W2039836948 hasConcept C73588182 @default.
- W2039836948 hasConcept C81089528 @default.
- W2039836948 hasConcept C86803240 @default.
- W2039836948 hasConcept C8891405 @default.
- W2039836948 hasConceptScore W2039836948C147483822 @default.
- W2039836948 hasConceptScore W2039836948C147969180 @default.
- W2039836948 hasConceptScore W2039836948C153911025 @default.
- W2039836948 hasConceptScore W2039836948C154317977 @default.
- W2039836948 hasConceptScore W2039836948C159047783 @default.
- W2039836948 hasConceptScore W2039836948C159654299 @default.
- W2039836948 hasConceptScore W2039836948C167672396 @default.
- W2039836948 hasConceptScore W2039836948C202751555 @default.
- W2039836948 hasConceptScore W2039836948C203014093 @default.
- W2039836948 hasConceptScore W2039836948C2777371288 @default.
- W2039836948 hasConceptScore W2039836948C2780931953 @default.
- W2039836948 hasConceptScore W2039836948C2992881475 @default.
- W2039836948 hasConceptScore W2039836948C49382859 @default.
- W2039836948 hasConceptScore W2039836948C542903549 @default.
- W2039836948 hasConceptScore W2039836948C54355233 @default.
- W2039836948 hasConceptScore W2039836948C552990157 @default.
- W2039836948 hasConceptScore W2039836948C73588182 @default.
- W2039836948 hasConceptScore W2039836948C81089528 @default.
- W2039836948 hasConceptScore W2039836948C86803240 @default.
- W2039836948 hasConceptScore W2039836948C8891405 @default.
- W2039836948 hasIssue "12" @default.
- W2039836948 hasLocation W20398369481 @default.
- W2039836948 hasLocation W20398369482 @default.
- W2039836948 hasOpenAccess W2039836948 @default.
- W2039836948 hasPrimaryLocation W20398369481 @default.
- W2039836948 hasRelatedWork W1970958732 @default.
- W2039836948 hasRelatedWork W1972127474 @default.
- W2039836948 hasRelatedWork W1994736304 @default.
- W2039836948 hasRelatedWork W2008093705 @default.
- W2039836948 hasRelatedWork W2055209622 @default.
- W2039836948 hasRelatedWork W2060850840 @default.
- W2039836948 hasRelatedWork W2101929599 @default.
- W2039836948 hasRelatedWork W2154231836 @default.
- W2039836948 hasRelatedWork W2513724291 @default.
- W2039836948 hasRelatedWork W4242443756 @default.
- W2039836948 hasVolume "3" @default.
- W2039836948 isParatext "false" @default.
- W2039836948 isRetracted "false" @default.
- W2039836948 magId "2039836948" @default.
- W2039836948 workType "article" @default.