Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039841202> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2039841202 endingPage "69" @default.
- W2039841202 startingPage "67" @default.
- W2039841202 abstract "The enzymes adenosine 3′,5′-monophosphate (cAMP)-dependent protein kinase (protein kinase A) and protein kinase C regulate the activity of a diverse group of cellular proteins including membrane ion channel proteins. When protein kinase A was stimulated in cardiac ventricular myocytes with the membrane-soluble cAMP analog 8-chlorphenylthio cAMP (8-CPT cAMP), the amplitude of the delayed-rectifier potassium current (IK) doubled when recorded at 32°C but was not affected at 22°C. In contrast, modulation of the calcium current (ICa) by 8-CPT cAMP was independent of temperature with similar increases in ICa occurring at both temperatures. Stimulation of protein kinase C by phorbol 12,13-dibutyrate also enhanced IK in a temperature-dependent manner but failed to increase ICa at either temperature. Thus, cardiac delayed-rectifier potassium but not calcium channels are regulated by two distinct protein kinases in a similar temperature-dependent fashion." @default.
- W2039841202 created "2016-06-24" @default.
- W2039841202 creator A5069088638 @default.
- W2039841202 creator A5085075737 @default.
- W2039841202 date "1988-10-07" @default.
- W2039841202 modified "2023-09-25" @default.
- W2039841202 title "Regulation of a Heart Potassium Channel by Protein Kinase A and C" @default.
- W2039841202 cites W1559814842 @default.
- W2039841202 cites W1964839077 @default.
- W2039841202 cites W1974736754 @default.
- W2039841202 cites W1998609823 @default.
- W2039841202 cites W2001692359 @default.
- W2039841202 cites W2002021305 @default.
- W2039841202 cites W2013011061 @default.
- W2039841202 cites W2018149328 @default.
- W2039841202 cites W2034637528 @default.
- W2039841202 cites W2040931773 @default.
- W2039841202 cites W2042217106 @default.
- W2039841202 cites W2055126132 @default.
- W2039841202 cites W2082910935 @default.
- W2039841202 cites W2093994141 @default.
- W2039841202 doi "https://doi.org/10.1126/science.2845575" @default.
- W2039841202 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2845575" @default.
- W2039841202 hasPublicationYear "1988" @default.
- W2039841202 type Work @default.
- W2039841202 sameAs 2039841202 @default.
- W2039841202 citedByCount "297" @default.
- W2039841202 countsByYear W20398412022012 @default.
- W2039841202 countsByYear W20398412022013 @default.
- W2039841202 countsByYear W20398412022014 @default.
- W2039841202 countsByYear W20398412022015 @default.
- W2039841202 countsByYear W20398412022016 @default.
- W2039841202 countsByYear W20398412022017 @default.
- W2039841202 countsByYear W20398412022018 @default.
- W2039841202 countsByYear W20398412022020 @default.
- W2039841202 countsByYear W20398412022021 @default.
- W2039841202 crossrefType "journal-article" @default.
- W2039841202 hasAuthorship W2039841202A5069088638 @default.
- W2039841202 hasAuthorship W2039841202A5085075737 @default.
- W2039841202 hasConcept C12554922 @default.
- W2039841202 hasConcept C170493617 @default.
- W2039841202 hasConcept C184235292 @default.
- W2039841202 hasConcept C185592680 @default.
- W2039841202 hasConcept C195794163 @default.
- W2039841202 hasConcept C199217515 @default.
- W2039841202 hasConcept C2776668983 @default.
- W2039841202 hasConcept C50254741 @default.
- W2039841202 hasConcept C55493867 @default.
- W2039841202 hasConcept C83743174 @default.
- W2039841202 hasConcept C86803240 @default.
- W2039841202 hasConcept C90934575 @default.
- W2039841202 hasConcept C94924445 @default.
- W2039841202 hasConcept C95444343 @default.
- W2039841202 hasConcept C97029542 @default.
- W2039841202 hasConceptScore W2039841202C12554922 @default.
- W2039841202 hasConceptScore W2039841202C170493617 @default.
- W2039841202 hasConceptScore W2039841202C184235292 @default.
- W2039841202 hasConceptScore W2039841202C185592680 @default.
- W2039841202 hasConceptScore W2039841202C195794163 @default.
- W2039841202 hasConceptScore W2039841202C199217515 @default.
- W2039841202 hasConceptScore W2039841202C2776668983 @default.
- W2039841202 hasConceptScore W2039841202C50254741 @default.
- W2039841202 hasConceptScore W2039841202C55493867 @default.
- W2039841202 hasConceptScore W2039841202C83743174 @default.
- W2039841202 hasConceptScore W2039841202C86803240 @default.
- W2039841202 hasConceptScore W2039841202C90934575 @default.
- W2039841202 hasConceptScore W2039841202C94924445 @default.
- W2039841202 hasConceptScore W2039841202C95444343 @default.
- W2039841202 hasConceptScore W2039841202C97029542 @default.
- W2039841202 hasIssue "4875" @default.
- W2039841202 hasLocation W20398412021 @default.
- W2039841202 hasLocation W20398412022 @default.
- W2039841202 hasOpenAccess W2039841202 @default.
- W2039841202 hasPrimaryLocation W20398412021 @default.
- W2039841202 hasRelatedWork W1490823055 @default.
- W2039841202 hasRelatedWork W1525517292 @default.
- W2039841202 hasRelatedWork W1965209261 @default.
- W2039841202 hasRelatedWork W1978256006 @default.
- W2039841202 hasRelatedWork W1983837106 @default.
- W2039841202 hasRelatedWork W2036777733 @default.
- W2039841202 hasRelatedWork W2039841202 @default.
- W2039841202 hasRelatedWork W2053278288 @default.
- W2039841202 hasRelatedWork W2132433659 @default.
- W2039841202 hasRelatedWork W2392603373 @default.
- W2039841202 hasVolume "242" @default.
- W2039841202 isParatext "false" @default.
- W2039841202 isRetracted "false" @default.
- W2039841202 magId "2039841202" @default.
- W2039841202 workType "article" @default.