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• W2039868621 abstract "Oral lichen planus (OLP) is a chronic disease with bandlike lymphocyte infiltration.To elucidate the immunologic phenotype of OLP, we analyzed the presence of CD5(+), CD20(+), CD27(+) and/or CD38(+) lymphocytes in a series of 70 atrophic OLP biopsy samples.CD27(+) and CD38(+) cells were present in 84% and 54% of the lesions, respectively. The lesions were graded as T-cell dominant, B-cell dominant, or a mixed lesion based on CD5(+) and CD20(+) cells in the inflammatory infiltration with the following results: 26%, 7%, and 67%, respectively. CD27 expression was found in 67% of the T-cell dominant, in 80% of the B-cell dominant, and in 91% of mixed lesions. The corresponding figures for CD38 were 72%, 80%, and 62%.CD27(+) and CD38(+) lymphocytes represent abnormal mononuclear cell populations in atrophic OLP lesions indicating 2 forms of OLP might exist with different pathogenesis, despite similar histology and clinical behavior." @default.
• W2039868621 created "2016-06-24" @default.
• W2039868621 creator A5030107910 @default.
• W2039868621 creator A5052490861 @default.
• W2039868621 creator A5089277822 @default.
• W2039868621 date "2011-02-01" @default.
• W2039868621 modified "2023-09-26" @default.
• W2039868621 title "CD27 and CD38 lymphocytes are detected in oral lichen planus lesions" @default.
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• W2039868621 doi "https://doi.org/10.1016/j.tripleo.2010.09.075" @default.
• W2039868621 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21237436" @default.
• W2039868621 hasPublicationYear "2011" @default.
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