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- W2039898082 abstract "Introduction Malaria still represents an important health problem for all companies which operate in high-risk malaria areas. Different malaria management strategies have been developed, most of them focused especially on prevention. Among malaria preventive measures, chemoprophylaxis is considered to be the most efficacious 1. Its effectiveness is estimated to about 93%2. That means that approximate 7% from exposed people to malaria could get the disease instead of taking chemoprophylaxis. The key point of chemoprophylaxis effectiveness is represented by the individual compliance, especially when a long lasting regimen is necessary 3. Individual compliance could be reinforced using many methods. Among them, the policy of compulsory anti-malarial chemoprophylaxis (further called compulsory regimen) is frequently applied to employees. This kind of measure seems to be benefic for onshore activities but its advantage is disputable when is applied for offshore activities. Some authors suggest that taking anti-malarial medications only prior to travel may prevent more possible malarial events by improving traveler's compliance 4. Moreover, the improper use of anti-malarial drugs is direct related to increased resistance of Plasmodium species to available drugs 5. Statement of Theory and Definitions Research question: The main purpose of present study is to determine a possible association between malaria incidence, respectively Malaria Case Rate (MCR) and anti-malarial chemoprophylaxis used for offshore activities. If chemoprophylaxis represents a real protective factor for offshore activities, it is expected that the incidence of malaria, respectively MCR, of the compulsory regimen group be lower than those of non compulsory regimen group. A retrospective cohort study was designed in order to asses this hypothesis." @default.
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- W2039898082 date "2008-04-15" @default.
- W2039898082 modified "2023-10-16" @default.
- W2039898082 title "The Benefits Of Anti-Malarial Chemoprophylaxis Concerning Off Shore Activities In High-Risk Malaria Areas." @default.
- W2039898082 doi "https://doi.org/10.2118/111444-ms" @default.
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