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- W2039944900 abstract "Detection of HPV-DNA in squamous vulvar carcinoma, its prognostic significance, and investigation of the presence of lichen sclerosus near HPV-DNA-positive vulvar carcinomas were the objectives of this study. In 60 samples of squamous vulvar cancer, we looked for HPV-DNA by means of PCR. The same samples were examined for the presence of lichen sclerosus. The possible prognostic significance of the presence of HPV-DNA and lichen sclerosus was studied. Nineteen (32%) of the samples were HPV-DNA positive using PCR. Patients with an HPV-positive tumor had a better prognosis than those with an HPV-negative tumor (P = 0.03). Lichen sclerosus was found in 19 tumor samples, of which 7 had detectable HPV-DNA. Only a minority of vulvar cancers contain HPV-DNA. In contrast to previous statements, near some of these HPV-positive cancers, lichen sclerosus can be found." @default.
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- W2039944900 date "1994-02-01" @default.
- W2039944900 modified "2023-10-02" @default.
- W2039944900 title "Human Papillomavirus, Lichen Sclerosus, and Squamous Cell Carcinoma of the Vulva: Detection and Prognostic Significance" @default.
- W2039944900 doi "https://doi.org/10.1006/gyno.1994.1028" @default.
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