Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039947995> ?p ?o ?g. }
- W2039947995 endingPage "1012" @default.
- W2039947995 startingPage "1005" @default.
- W2039947995 abstract "pH variations in the retina are thought to be involved in the fine-tuning of visual perception. We show that both photoreceptors and neurons of the mouse retina express the H + -gated cation channel subunits acid-sensing ion channel 2a (ASIC2a) and ASIC2b. Inactivation of the ASIC2 gene in mice leads to an increase in the rod electroretinogram a- and b-waves and thus to an enhanced gain of visual transduction. ASIC2 knock-out mice are also more sensitive to light-induced retinal degeneration. We suggest that ASIC2 is a negative modulator of rod phototransduction, and that functional ASIC2 channels are beneficial for the maintenance of retinal integrity." @default.
- W2039947995 created "2016-06-24" @default.
- W2039947995 creator A5026966948 @default.
- W2039947995 creator A5043727019 @default.
- W2039947995 creator A5046273802 @default.
- W2039947995 creator A5068045779 @default.
- W2039947995 creator A5089171072 @default.
- W2039947995 date "2004-02-04" @default.
- W2039947995 modified "2023-10-15" @default.
- W2039947995 title "Acid-Sensing Ion Channel 2 Is Important for Retinal Function and Protects against Light-Induced Retinal Degeneration" @default.
- W2039947995 cites W136054260 @default.
- W2039947995 cites W1516840674 @default.
- W2039947995 cites W152754957 @default.
- W2039947995 cites W1528778201 @default.
- W2039947995 cites W1546862061 @default.
- W2039947995 cites W185100356 @default.
- W2039947995 cites W1852983420 @default.
- W2039947995 cites W1893444436 @default.
- W2039947995 cites W1906993142 @default.
- W2039947995 cites W1967255925 @default.
- W2039947995 cites W1974642350 @default.
- W2039947995 cites W1974805514 @default.
- W2039947995 cites W1978354972 @default.
- W2039947995 cites W1985723817 @default.
- W2039947995 cites W1986109085 @default.
- W2039947995 cites W1989289789 @default.
- W2039947995 cites W1993209115 @default.
- W2039947995 cites W1995661777 @default.
- W2039947995 cites W1997284957 @default.
- W2039947995 cites W1998564418 @default.
- W2039947995 cites W2002594079 @default.
- W2039947995 cites W2009199141 @default.
- W2039947995 cites W2016166286 @default.
- W2039947995 cites W2023963289 @default.
- W2039947995 cites W2025674004 @default.
- W2039947995 cites W2042725935 @default.
- W2039947995 cites W2047283239 @default.
- W2039947995 cites W205550050 @default.
- W2039947995 cites W2069680890 @default.
- W2039947995 cites W2070671106 @default.
- W2039947995 cites W2071302134 @default.
- W2039947995 cites W2082340545 @default.
- W2039947995 cites W2087002624 @default.
- W2039947995 cites W2092433412 @default.
- W2039947995 cites W2093660899 @default.
- W2039947995 cites W2119336577 @default.
- W2039947995 cites W2129742436 @default.
- W2039947995 cites W2138864044 @default.
- W2039947995 cites W2153283555 @default.
- W2039947995 cites W2184561450 @default.
- W2039947995 cites W4248514792 @default.
- W2039947995 doi "https://doi.org/10.1523/jneurosci.4698-03.2004" @default.
- W2039947995 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6793571" @default.
- W2039947995 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14762118" @default.
- W2039947995 hasPublicationYear "2004" @default.
- W2039947995 type Work @default.
- W2039947995 sameAs 2039947995 @default.
- W2039947995 citedByCount "101" @default.
- W2039947995 countsByYear W20399479952012 @default.
- W2039947995 countsByYear W20399479952013 @default.
- W2039947995 countsByYear W20399479952014 @default.
- W2039947995 countsByYear W20399479952015 @default.
- W2039947995 countsByYear W20399479952016 @default.
- W2039947995 countsByYear W20399479952017 @default.
- W2039947995 countsByYear W20399479952018 @default.
- W2039947995 countsByYear W20399479952019 @default.
- W2039947995 countsByYear W20399479952020 @default.
- W2039947995 countsByYear W20399479952021 @default.
- W2039947995 countsByYear W20399479952022 @default.
- W2039947995 countsByYear W20399479952023 @default.
- W2039947995 crossrefType "journal-article" @default.
- W2039947995 hasAuthorship W2039947995A5026966948 @default.
- W2039947995 hasAuthorship W2039947995A5043727019 @default.
- W2039947995 hasAuthorship W2039947995A5046273802 @default.
- W2039947995 hasAuthorship W2039947995A5068045779 @default.
- W2039947995 hasAuthorship W2039947995A5089171072 @default.
- W2039947995 hasBestOaLocation W20399479951 @default.
- W2039947995 hasConcept C12554922 @default.
- W2039947995 hasConcept C131667965 @default.
- W2039947995 hasConcept C143928317 @default.
- W2039947995 hasConcept C15152581 @default.
- W2039947995 hasConcept C169760540 @default.
- W2039947995 hasConcept C170493617 @default.
- W2039947995 hasConcept C185263204 @default.
- W2039947995 hasConcept C2777093970 @default.
- W2039947995 hasConcept C2780827179 @default.
- W2039947995 hasConcept C2781040256 @default.
- W2039947995 hasConcept C50254741 @default.
- W2039947995 hasConcept C55493867 @default.
- W2039947995 hasConcept C86803240 @default.
- W2039947995 hasConcept C95444343 @default.
- W2039947995 hasConceptScore W2039947995C12554922 @default.
- W2039947995 hasConceptScore W2039947995C131667965 @default.
- W2039947995 hasConceptScore W2039947995C143928317 @default.
- W2039947995 hasConceptScore W2039947995C15152581 @default.
- W2039947995 hasConceptScore W2039947995C169760540 @default.
- W2039947995 hasConceptScore W2039947995C170493617 @default.
- W2039947995 hasConceptScore W2039947995C185263204 @default.