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- W2039969107 endingPage "925" @default.
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- W2039969107 abstract "Physiological and pathophysiological roles of K(ATP) channels have been clarified recently in genetically engineered mice. The Kir6.2-containing K(ATP) channels in pancreatic ss-cells and the hypothalamus are essential in the regulation of glucose-induced insulin secretion and hypoglycemia-induced glucagon secretion, respectively, and are involved in glucose uptake in skeletal muscles, thus playing a key role in the maintenance of glucose homeostasis. Disruption of Kir6.1-containing K(ATP) channels in mice leads to spontaneous vascular spasm mimicking vasospastic (Prinzmetal) angina in humans, indicating that the Kir6.1-containing K(ATP) channels in vascular smooth muscles participate in the regulation of vascular tonus, especially in coronary arteries. Together with protective roles of K(ATP) channels against cardiac ischemia and hypoxia-induced seizure propagation, it is now clear that K(ATP) channels, as metabolic sensors, are critical in the maintenance of homeostasis against acute metabolic changes." @default.
- W2039969107 created "2016-06-24" @default.
- W2039969107 creator A5028420497 @default.
- W2039969107 creator A5046353080 @default.
- W2039969107 date "2005-06-01" @default.
- W2039969107 modified "2023-09-25" @default.
- W2039969107 title "Roles of KATP channels as metabolic sensors in acute metabolic changes" @default.
- W2039969107 cites W1487837909 @default.
- W2039969107 cites W1535426243 @default.
- W2039969107 cites W1539435207 @default.
- W2039969107 cites W1555144527 @default.
- W2039969107 cites W1561443084 @default.
- W2039969107 cites W1562122315 @default.
- W2039969107 cites W1623365227 @default.
- W2039969107 cites W1632767742 @default.
- W2039969107 cites W1749560786 @default.
- W2039969107 cites W1866620858 @default.
- W2039969107 cites W1901856024 @default.
- W2039969107 cites W1967307504 @default.
- W2039969107 cites W1967916919 @default.
- W2039969107 cites W1968750290 @default.
- W2039969107 cites W1972400285 @default.
- W2039969107 cites W1977054557 @default.
- W2039969107 cites W1977796924 @default.
- W2039969107 cites W1978469530 @default.
- W2039969107 cites W1980007713 @default.
- W2039969107 cites W1980347800 @default.
- W2039969107 cites W1982324844 @default.
- W2039969107 cites W1986804446 @default.
- W2039969107 cites W1990845205 @default.
- W2039969107 cites W1992045485 @default.
- W2039969107 cites W1993854078 @default.
- W2039969107 cites W1999285748 @default.
- W2039969107 cites W2000115601 @default.
- W2039969107 cites W2010320641 @default.
- W2039969107 cites W2012515461 @default.
- W2039969107 cites W2015001567 @default.
- W2039969107 cites W2019024229 @default.
- W2039969107 cites W2029375255 @default.
- W2039969107 cites W2029414905 @default.
- W2039969107 cites W2030973682 @default.
- W2039969107 cites W2034158559 @default.
- W2039969107 cites W2034772537 @default.
- W2039969107 cites W2037028566 @default.
- W2039969107 cites W2040593177 @default.
- W2039969107 cites W2042194920 @default.
- W2039969107 cites W2046421235 @default.
- W2039969107 cites W2048268426 @default.
- W2039969107 cites W2050051162 @default.
- W2039969107 cites W2050342883 @default.
- W2039969107 cites W2054704723 @default.
- W2039969107 cites W2057328350 @default.
- W2039969107 cites W2062346208 @default.
- W2039969107 cites W2066650398 @default.
- W2039969107 cites W2067050387 @default.
- W2039969107 cites W2067381761 @default.
- W2039969107 cites W2067935663 @default.
- W2039969107 cites W2069063507 @default.
- W2039969107 cites W2071511621 @default.
- W2039969107 cites W2071589836 @default.
- W2039969107 cites W2074306054 @default.
- W2039969107 cites W2075761723 @default.
- W2039969107 cites W2077230920 @default.
- W2039969107 cites W2077873945 @default.
- W2039969107 cites W2080766203 @default.
- W2039969107 cites W2081764386 @default.
- W2039969107 cites W2083584165 @default.
- W2039969107 cites W2086091325 @default.
- W2039969107 cites W2086345475 @default.
- W2039969107 cites W2086605260 @default.
- W2039969107 cites W2087577070 @default.
- W2039969107 cites W2091810508 @default.
- W2039969107 cites W2096308603 @default.
- W2039969107 cites W2104214122 @default.
- W2039969107 cites W2108134904 @default.
- W2039969107 cites W2110015701 @default.
- W2039969107 cites W2122568821 @default.
- W2039969107 cites W2124971376 @default.
- W2039969107 cites W2125905134 @default.
- W2039969107 cites W2127969072 @default.
- W2039969107 cites W2136251267 @default.
- W2039969107 cites W2139141874 @default.
- W2039969107 cites W2144882301 @default.
- W2039969107 cites W2145047166 @default.
- W2039969107 cites W2148255642 @default.
- W2039969107 cites W2154784838 @default.
- W2039969107 cites W2160723322 @default.
- W2039969107 cites W2164861152 @default.
- W2039969107 cites W2169174186 @default.
- W2039969107 cites W2236651085 @default.
- W2039969107 cites W2287333882 @default.
- W2039969107 cites W2321268350 @default.
- W2039969107 cites W2322041353 @default.
- W2039969107 cites W2330339020 @default.
- W2039969107 cites W2334369162 @default.
- W2039969107 cites W2417651328 @default.
- W2039969107 cites W4231136008 @default.
- W2039969107 doi "https://doi.org/10.1016/j.yjmcc.2004.11.019" @default.