FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2039969320> ?p ?o ?g. }

• W2039969320 endingPage "963" @default.
• W2039969320 startingPage "957" @default.
• W2039969320 abstract "Readily available D-erythro-azidosphingosine is transformed into 3-O-silyl-protected derivative 6. Reduction of the azido group afforded 3-O-silyl-protected sphingosine 7 which was either converted into N-Fmoc-protected derivative 8 or via N-acylation into ceramide derivatives 16 and 17, respectively. Treatment of 6, 8, and 16 with bis(2-cyanoethoxy)(diiso-propylamino)phosphane as monofunctional phosphitylating agent, subsequent oxidation and then removal of the protective groups furnished azidosphingosine-1-phosphate (11), sphingosine-1-phosphate (2), and ceramide-1-phosphate (4), respectively. Treatment of 8 and 17 with bis(diisopropyl-amino)(2-cyanoethoxy)phosphane as bifunctional phosphitylating agent and then with choline afforded after oxidation and subsequent deprotection lysosphingomyelin (3) and sphingomeylin (1), respectively in high overall yields. All final products are stereochemically pure and possess D-er-ythro configuration in the sphingosine moiety." @default.
• W2039969320 created "2016-06-24" @default.
• W2039969320 creator A5017914811 @default.
• W2039969320 creator A5038789569 @default.
• W2039969320 date "1995-06-01" @default.
• W2039969320 modified "2023-09-23" @default.
• W2039969320 title "Efficient synthesis of sphingosine-1-phosphate, ceramide-1-phosphate, lysosphingomyelin, and sphingomyelin" @default.
• W2039969320 cites W1510210099 @default.
• W2039969320 cites W1514747902 @default.
• W2039969320 cites W1519144352 @default.
• W2039969320 cites W1582592433 @default.
• W2039969320 cites W1726370369 @default.
• W2039969320 cites W1860613861 @default.
• W2039969320 cites W1979406683 @default.
• W2039969320 cites W1982632737 @default.
• W2039969320 cites W1982975958 @default.
• W2039969320 cites W1985912672 @default.
• W2039969320 cites W1986635894 @default.
• W2039969320 cites W1986666165 @default.
• W2039969320 cites W1992281959 @default.
• W2039969320 cites W1999114207 @default.
• W2039969320 cites W2000823512 @default.
• W2039969320 cites W2009316968 @default.
• W2039969320 cites W2009883597 @default.
• W2039969320 cites W2009993180 @default.
• W2039969320 cites W2012806651 @default.
• W2039969320 cites W2014664200 @default.
• W2039969320 cites W2017729786 @default.
• W2039969320 cites W2030065963 @default.
• W2039969320 cites W2031130248 @default.
• W2039969320 cites W2037167609 @default.
• W2039969320 cites W2039753367 @default.
• W2039969320 cites W2050396995 @default.
• W2039969320 cites W2057254779 @default.
• W2039969320 cites W2057399985 @default.
• W2039969320 cites W2061574494 @default.
• W2039969320 cites W2065905915 @default.
• W2039969320 cites W2066298940 @default.
• W2039969320 cites W2075503855 @default.
• W2039969320 cites W2078480020 @default.
• W2039969320 cites W2081200884 @default.
• W2039969320 cites W2081626050 @default.
• W2039969320 cites W2094588396 @default.
• W2039969320 cites W2130706989 @default.
• W2039969320 cites W2145926815 @default.
• W2039969320 cites W2159811088 @default.
• W2039969320 cites W2188743217 @default.
• W2039969320 cites W2317481232 @default.
• W2039969320 cites W2322132040 @default.
• W2039969320 cites W2322290186 @default.
• W2039969320 cites W2337174023 @default.
• W2039969320 cites W2994274744 @default.
• W2039969320 cites W4256062136 @default.
• W2039969320 doi "https://doi.org/10.1002/jlac.1995199506137" @default.
• W2039969320 hasPublicationYear "1995" @default.
• W2039969320 type Work @default.
• W2039969320 sameAs 2039969320 @default.
• W2039969320 citedByCount "12" @default.
• W2039969320 crossrefType "journal-article" @default.
• W2039969320 hasAuthorship W2039969320A5017914811 @default.
• W2039969320 hasAuthorship W2039969320A5038789569 @default.
• W2039969320 hasConcept C106159729 @default.
• W2039969320 hasConcept C111771559 @default.
• W2039969320 hasConcept C161790260 @default.
• W2039969320 hasConcept C162324750 @default.
• W2039969320 hasConcept C170493617 @default.
• W2039969320 hasConcept C185592680 @default.
• W2039969320 hasConcept C190283241 @default.
• W2039969320 hasConcept C193557335 @default.
• W2039969320 hasConcept C21951064 @default.
• W2039969320 hasConcept C2776568683 @default.
• W2039969320 hasConcept C2776596873 @default.
• W2039969320 hasConcept C2777132085 @default.
• W2039969320 hasConcept C2777851122 @default.
• W2039969320 hasConcept C2778703144 @default.
• W2039969320 hasConcept C2780443040 @default.
• W2039969320 hasConcept C41625074 @default.
• W2039969320 hasConcept C5304478 @default.
• W2039969320 hasConcept C55493867 @default.
• W2039969320 hasConcept C61322309 @default.
• W2039969320 hasConcept C71240020 @default.
• W2039969320 hasConceptScore W2039969320C106159729 @default.
• W2039969320 hasConceptScore W2039969320C111771559 @default.
• W2039969320 hasConceptScore W2039969320C161790260 @default.
• W2039969320 hasConceptScore W2039969320C162324750 @default.
• W2039969320 hasConceptScore W2039969320C170493617 @default.
• W2039969320 hasConceptScore W2039969320C185592680 @default.
• W2039969320 hasConceptScore W2039969320C190283241 @default.
• W2039969320 hasConceptScore W2039969320C193557335 @default.
• W2039969320 hasConceptScore W2039969320C21951064 @default.
• W2039969320 hasConceptScore W2039969320C2776568683 @default.
• W2039969320 hasConceptScore W2039969320C2776596873 @default.
• W2039969320 hasConceptScore W2039969320C2777132085 @default.
• W2039969320 hasConceptScore W2039969320C2777851122 @default.
• W2039969320 hasConceptScore W2039969320C2778703144 @default.
• W2039969320 hasConceptScore W2039969320C2780443040 @default.
• W2039969320 hasConceptScore W2039969320C41625074 @default.
• W2039969320 hasConceptScore W2039969320C5304478 @default.

• next