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- W2039971262 abstract "Hydroquinone-O,O′-diacetic acid (QDA) can be used to link nucleosides to CPG or polystyrene supports instead of succinic acid. Cleavage of oligodeoxy- or oligoribonucleotides, using ammonium hydroxide, requires only two to five minutes. The QDA linker is stable, easily prepared and does not require any other changes to the reagents, methods, or instrumentation used in automated solid-phase oligonucleotide synthesis." @default.
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- W2039971262 date "1997-05-01" @default.
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- W2039971262 title "Hydroquinone-O,O′-diacetic acid as a more labile replacement for succinic acid linkers in solid-phase oligonucleotide synthesis" @default.
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- W2039971262 doi "https://doi.org/10.1016/s0040-4039(97)00619-9" @default.
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