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- W2040000334 abstract "Marchioli et al.1 report in the Journal that a hematocrit target of less than 45% for therapeutic phlebotomy reduces the risk of thrombosis in patients with polycythemia vera. In the genomic era, readers may question attention given to a measurement as mundane as the hematocrit, but this study resolves a half-century of debate about the role of phlebotomy in polycythemia vera and has ramifications for diagnosis and management.Polycythemia vera is a unique myeloproliferative disorder in which there is overproduction of morphologically normal erythrocytes, granulocytes, and platelets, a phenotype that is caused by a mutation (V617F) in JAK2, encoding a . . ." @default.
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- W2040000334 date "2013-01-03" @default.
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- W2040000334 title "Polycythemia Vera, the Hematocrit, and Blood-Volume Physiology" @default.
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- W2040000334 doi "https://doi.org/10.1056/nejme1213283" @default.
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