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- W2040063779 abstract "Abstract 1. 1. Rectangular current pulses were applied to the soma of neurones in Helix aspersa through intracellular electrodes. The frequency response to a conditioning depolarization adapted during prolonged stimuli. 2. 2. The properties of adaptation in most cells fell between two extremes: the phasic type behaviour, in which the frequency was reduced by a similar extent at all current strengths, and the tonic type, in which adaptation was greater at high current strengths and there was a tendency towards a maximum resting rate of firing. 3. 3. Large increases in AP duration, particularly in the falling phase, took place in cells showing tonic-type adaptation. This was accompanied by a high-resistance plateau formation and increase in the firing threshold. There was relatively little change in the action potentials in cells displaying phasictype adaptation. 4. 4. Adaptation bore a relationship with after-hyperpolarization amplitude. The relationship divided the cells into two populations with greater or lesser adaptation for a given after-potential size. 5. 5. Results were discussed in terms of two separate mechanisms which might influence the degree of adaptation of response in the neurones." @default.
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- W2040063779 date "1978-01-01" @default.
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- W2040063779 title "Relationship of ap frequency adaptation to the size of after-hyperpolarization and to membrane conductivity in neurones of Helix aspersa" @default.
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- W2040063779 doi "https://doi.org/10.1016/0300-9629(78)90042-7" @default.
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