FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040091575> ?p ?o ?g. }

• W2040091575 endingPage "1717" @default.
• W2040091575 startingPage "1714" @default.
• W2040091575 abstract "The HIV reverse transcriptase (RT) is an important antiviral target for the chemotherapy of AIDS because of its key role in virus replication. Nevirapine is a first generation of non-nucleoside reverse transcriptase inhibitors (NNRTIs), which is usually used for the therapy of AIDS. In this study, a high-performance analytical method based on capillary electrophoresis (CE) to investigate interactions between HIV RT and nevirapine was developed. Samples containing HIV RT and nevirapine at various ratios were incubated at 37 degrees C for 45 min and then separated by CE with Tris-acetate buffer at pH 7.3 containing 0.15% SDS. Both qualitative and quantitative characterizations of the binding were determined by CE for the first time. The binding constants of the interactions between HIV RT and nevirapine were calculated as (3.25+/-0.16)x10(4) and (1.25+/-0.07)x10(2) M(-1) by Scatchard analysis. HIV RT and nevirapine have two binding sites. The presented methodology should be generally applicable to study the interactions between HIV RT and nevirapine quantitatively and qualitatively." @default.
• W2040091575 created "2016-06-24" @default.
• W2040091575 creator A5068147366 @default.
• W2040091575 creator A5069798447 @default.
• W2040091575 creator A5070317590 @default.
• W2040091575 creator A5071626568 @default.
• W2040091575 creator A5090270861 @default.
• W2040091575 date "2010-06-01" @default.
• W2040091575 modified "2023-10-17" @default.
• W2040091575 title "Study on the interaction between HIV reverse transcriptase and its non-nucleoside inhibitor nevirapine by capillary electrophoresis" @default.
• W2040091575 cites W1968258393 @default.
• W2040091575 cites W1971915605 @default.
• W2040091575 cites W1976173140 @default.
• W2040091575 cites W1983649348 @default.
• W2040091575 cites W1988315614 @default.
• W2040091575 cites W1992075564 @default.
• W2040091575 cites W2004207630 @default.
• W2040091575 cites W2026154865 @default.
• W2040091575 cites W2026379734 @default.
• W2040091575 cites W2039971096 @default.
• W2040091575 cites W2040679107 @default.
• W2040091575 cites W2044645968 @default.
• W2040091575 cites W2048513928 @default.
• W2040091575 cites W2050600072 @default.
• W2040091575 cites W2054044810 @default.
• W2040091575 cites W2058708854 @default.
• W2040091575 cites W2060541152 @default.
• W2040091575 cites W2071394033 @default.
• W2040091575 cites W2073829104 @default.
• W2040091575 cites W2117064497 @default.
• W2040091575 cites W2161318075 @default.
• W2040091575 cites W2166782710 @default.
• W2040091575 doi "https://doi.org/10.1016/j.jchromb.2010.04.013" @default.
• W2040091575 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20457546" @default.
• W2040091575 hasPublicationYear "2010" @default.
• W2040091575 type Work @default.
• W2040091575 sameAs 2040091575 @default.
• W2040091575 citedByCount "10" @default.
• W2040091575 countsByYear W20400915752012 @default.
• W2040091575 countsByYear W20400915752013 @default.
• W2040091575 countsByYear W20400915752015 @default.
• W2040091575 countsByYear W20400915752016 @default.
• W2040091575 countsByYear W20400915752017 @default.
• W2040091575 countsByYear W20400915752020 @default.
• W2040091575 crossrefType "journal-article" @default.
• W2040091575 hasAuthorship W2040091575A5068147366 @default.
• W2040091575 hasAuthorship W2040091575A5069798447 @default.
• W2040091575 hasAuthorship W2040091575A5070317590 @default.
• W2040091575 hasAuthorship W2040091575A5071626568 @default.
• W2040091575 hasAuthorship W2040091575A5090270861 @default.
• W2040091575 hasConcept C104317684 @default.
• W2040091575 hasConcept C142462285 @default.
• W2040091575 hasConcept C156719811 @default.
• W2040091575 hasConcept C159047783 @default.
• W2040091575 hasConcept C185592680 @default.
• W2040091575 hasConcept C2776543447 @default.
• W2040091575 hasConcept C2777333352 @default.
• W2040091575 hasConcept C2777351918 @default.
• W2040091575 hasConcept C2779130552 @default.
• W2040091575 hasConcept C2780216070 @default.
• W2040091575 hasConcept C2780727368 @default.
• W2040091575 hasConcept C2900643 @default.
• W2040091575 hasConcept C2909970146 @default.
• W2040091575 hasConcept C2993143319 @default.
• W2040091575 hasConcept C3013748606 @default.
• W2040091575 hasConcept C43617362 @default.
• W2040091575 hasConcept C55493867 @default.
• W2040091575 hasConcept C67705224 @default.
• W2040091575 hasConcept C71240020 @default.
• W2040091575 hasConcept C86803240 @default.
• W2040091575 hasConceptScore W2040091575C104317684 @default.
• W2040091575 hasConceptScore W2040091575C142462285 @default.
• W2040091575 hasConceptScore W2040091575C156719811 @default.
• W2040091575 hasConceptScore W2040091575C159047783 @default.
• W2040091575 hasConceptScore W2040091575C185592680 @default.
• W2040091575 hasConceptScore W2040091575C2776543447 @default.
• W2040091575 hasConceptScore W2040091575C2777333352 @default.
• W2040091575 hasConceptScore W2040091575C2777351918 @default.
• W2040091575 hasConceptScore W2040091575C2779130552 @default.
• W2040091575 hasConceptScore W2040091575C2780216070 @default.
• W2040091575 hasConceptScore W2040091575C2780727368 @default.
• W2040091575 hasConceptScore W2040091575C2900643 @default.
• W2040091575 hasConceptScore W2040091575C2909970146 @default.
• W2040091575 hasConceptScore W2040091575C2993143319 @default.
• W2040091575 hasConceptScore W2040091575C3013748606 @default.
• W2040091575 hasConceptScore W2040091575C43617362 @default.
• W2040091575 hasConceptScore W2040091575C55493867 @default.
• W2040091575 hasConceptScore W2040091575C67705224 @default.
• W2040091575 hasConceptScore W2040091575C71240020 @default.
• W2040091575 hasConceptScore W2040091575C86803240 @default.
• W2040091575 hasIssue "20" @default.
• W2040091575 hasLocation W20400915751 @default.
• W2040091575 hasLocation W20400915752 @default.
• W2040091575 hasOpenAccess W2040091575 @default.
• W2040091575 hasPrimaryLocation W20400915751 @default.
• W2040091575 hasRelatedWork W2026564608 @default.
• W2040091575 hasRelatedWork W2079935130 @default.
• W2040091575 hasRelatedWork W2087889515 @default.

• next