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• W2040142005 abstract "ObjectiveTo analyse clinical pregnancy and implantation rates of identical fresh and frozen blastocyst transfers, through an innovative matched-paired comparison.DesignA retrospective analysis of 393 fresh and 200 frozen blastocyst transfers, performed between 2010 and 2013.Materials and MethodsAll frozen blastocyst were vitrified and warmed using the Kitazato Cryotop method. Oocytes for the fresh replacement of blastocysts were obtained by antagonist controlled ovarian stimulation protocol. Blastocyst scoring followed the classical scoring system of stage of development (1-6 scale), inner cell mass (A-C scale) and trophectoderm (A-C scale). Only single and double replacements were included in the analysis. A computer generated matrix was constructed matching blastocyst replacements exactly by number replaced and blastocyst score; (eg, d54AAd53AB fresh vs d54AAd53AB frozen).ResultsTabled 1freshfrozen+p-valueage (yrs)30±5.1930±5.23p=1.000 (t-test)# replacements407206# pregnancies (%)249 (61.8)128 (62.1)p=0.944 (χ2 test)# blastocysts replaced755350# fetal sacs (%*)321 (42.5)134 (38.3)p=0.206 (χ2 test)* implantation rate is defined as a fetal sac at 7 week ultrasound examination. Open table in a new tab ConclusionOur blastocyst program shows that if blastocyst quality is absolutely controlled for according to the classical blastocyst scoring system there are no real differences in outcome between fresh and frozen embryo replacements. ObjectiveTo analyse clinical pregnancy and implantation rates of identical fresh and frozen blastocyst transfers, through an innovative matched-paired comparison. To analyse clinical pregnancy and implantation rates of identical fresh and frozen blastocyst transfers, through an innovative matched-paired comparison. DesignA retrospective analysis of 393 fresh and 200 frozen blastocyst transfers, performed between 2010 and 2013. A retrospective analysis of 393 fresh and 200 frozen blastocyst transfers, performed between 2010 and 2013. Materials and MethodsAll frozen blastocyst were vitrified and warmed using the Kitazato Cryotop method. Oocytes for the fresh replacement of blastocysts were obtained by antagonist controlled ovarian stimulation protocol. Blastocyst scoring followed the classical scoring system of stage of development (1-6 scale), inner cell mass (A-C scale) and trophectoderm (A-C scale). Only single and double replacements were included in the analysis. A computer generated matrix was constructed matching blastocyst replacements exactly by number replaced and blastocyst score; (eg, d54AAd53AB fresh vs d54AAd53AB frozen). All frozen blastocyst were vitrified and warmed using the Kitazato Cryotop method. Oocytes for the fresh replacement of blastocysts were obtained by antagonist controlled ovarian stimulation protocol. Blastocyst scoring followed the classical scoring system of stage of development (1-6 scale), inner cell mass (A-C scale) and trophectoderm (A-C scale). Only single and double replacements were included in the analysis. A computer generated matrix was constructed matching blastocyst replacements exactly by number replaced and blastocyst score; (eg, d54AAd53AB fresh vs d54AAd53AB frozen). ResultsTabled 1freshfrozen+p-valueage (yrs)30±5.1930±5.23p=1.000 (t-test)# replacements407206# pregnancies (%)249 (61.8)128 (62.1)p=0.944 (χ2 test)# blastocysts replaced755350# fetal sacs (%*)321 (42.5)134 (38.3)p=0.206 (χ2 test)* implantation rate is defined as a fetal sac at 7 week ultrasound examination. Open table in a new tab * implantation rate is defined as a fetal sac at 7 week ultrasound examination. ConclusionOur blastocyst program shows that if blastocyst quality is absolutely controlled for according to the classical blastocyst scoring system there are no real differences in outcome between fresh and frozen embryo replacements. Our blastocyst program shows that if blastocyst quality is absolutely controlled for according to the classical blastocyst scoring system there are no real differences in outcome between fresh and frozen embryo replacements." @default.
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• W2040142005 date "2013-09-01" @default.
• W2040142005 modified "2023-09-28" @default.
• W2040142005 title "Identical blastocyst scores yield equivalent pregnancy outcomes in fresh versus frozen cycles" @default.
• W2040142005 doi "https://doi.org/10.1016/j.fertnstert.2013.07.1407" @default.
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