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- W2040146043 abstract "Leu-enkephalin labelled with tritium in the Leu residue has been prepared. Synthesis of the precursor peptide, [4,5-dehydro Leu5-]Leu-enkephalin, was carried out by solid phase synthesis using Fmoc amino acid derivatives. The peptide was tritiated catalytically yielding 3H-Leu-enkephalin with a specific radioactivity of 4.39 TBq/mmol. The distribution of tritium label was investigated by reversed-phase high performance liquid chromatography with a synchronized accumulating radioisotope detector following acidic and enzymatic hydrolysis, which confirmed that the tritium label was entirely located at Leu residue." @default.
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- W2040146043 date "1989-12-01" @default.
- W2040146043 modified "2023-09-24" @default.
- W2040146043 title "Synthesis of high specific active tritiated Leu-enkephalin in the leucine residue" @default.
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- W2040146043 doi "https://doi.org/10.1002/jlcr.2580271203" @default.
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