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- W2040189671 abstract "In recent years, a stochastic model of cancer development and detection allowing for arbitrary screening schedules has been developed and applied to analysis of screening trials and population-based cancer incidence and mortality data. The model is entirely mechanistic, builds on a minimal set of biologically plausible assumptions, and yields the joint distribution of tumor size and age of a patient at the time of diagnosis. Whether or not parameters of the model can be estimated from data generated by cohort studies depends on model identifiability. The present paper provides a proof of this important property of the model." @default.
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- W2040189671 date "2007-08-01" @default.
- W2040189671 modified "2023-09-30" @default.
- W2040189671 title "Identifiability of the joint distribution of age and tumor size at detection in the presence of screening" @default.
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- W2040189671 doi "https://doi.org/10.1016/j.mbs.2006.12.004" @default.
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