Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040209654> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2040209654 endingPage "2509" @default.
- W2040209654 startingPage "2507" @default.
- W2040209654 abstract "This study was performed to explore the potential role of mitochondrial DNA mutations in the neurodegenerative process in amyotrophic lateral sclerosis (ALS). Using a semi-quantitative assay, a common mitochondrial DNA deletion mutation (mt DNA4977) was assayed in brain tissue obtained from six sporadic ALS patients and compared to four controls. In each brain, levels of this mutation were measured in a brain region affected by neurodegeneration, the motor cortex (Brodmann area 4), and compared to the temporal cortex (Brodmann area 17). In the ALS but not control brains, levels of mt DNA4977 were an average of more than 30-fold (range 15-250) higher in Brodmann area 4. These results support and extend those of previous studies implying that mitochondria may participate in the neurodegenerative process in ALS." @default.
- W2040209654 created "2016-06-24" @default.
- W2040209654 creator A5038962852 @default.
- W2040209654 creator A5058847503 @default.
- W2040209654 date "2000-08-01" @default.
- W2040209654 modified "2023-09-25" @default.
- W2040209654 title "Mitochondrial DNA deletion mutation levels are elevated in ALS brains" @default.
- W2040209654 cites W1535522275 @default.
- W2040209654 cites W1991548578 @default.
- W2040209654 cites W2009883535 @default.
- W2040209654 cites W2018185503 @default.
- W2040209654 cites W2036029971 @default.
- W2040209654 cites W2125501179 @default.
- W2040209654 doi "https://doi.org/10.1097/00001756-200008030-00032" @default.
- W2040209654 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10943712" @default.
- W2040209654 hasPublicationYear "2000" @default.
- W2040209654 type Work @default.
- W2040209654 sameAs 2040209654 @default.
- W2040209654 citedByCount "96" @default.
- W2040209654 countsByYear W20402096542012 @default.
- W2040209654 countsByYear W20402096542014 @default.
- W2040209654 countsByYear W20402096542015 @default.
- W2040209654 countsByYear W20402096542016 @default.
- W2040209654 countsByYear W20402096542017 @default.
- W2040209654 countsByYear W20402096542018 @default.
- W2040209654 countsByYear W20402096542019 @default.
- W2040209654 countsByYear W20402096542020 @default.
- W2040209654 countsByYear W20402096542021 @default.
- W2040209654 countsByYear W20402096542022 @default.
- W2040209654 countsByYear W20402096542023 @default.
- W2040209654 crossrefType "journal-article" @default.
- W2040209654 hasAuthorship W2040209654A5038962852 @default.
- W2040209654 hasAuthorship W2040209654A5058847503 @default.
- W2040209654 hasConcept C104317684 @default.
- W2040209654 hasConcept C142724271 @default.
- W2040209654 hasConcept C169760540 @default.
- W2040209654 hasConcept C24586158 @default.
- W2040209654 hasConcept C24998067 @default.
- W2040209654 hasConcept C2776925932 @default.
- W2040209654 hasConcept C2777348757 @default.
- W2040209654 hasConcept C2778373776 @default.
- W2040209654 hasConcept C2779134260 @default.
- W2040209654 hasConcept C2780596555 @default.
- W2040209654 hasConcept C2781041448 @default.
- W2040209654 hasConcept C28859421 @default.
- W2040209654 hasConcept C501734568 @default.
- W2040209654 hasConcept C54355233 @default.
- W2040209654 hasConcept C71924100 @default.
- W2040209654 hasConcept C86803240 @default.
- W2040209654 hasConceptScore W2040209654C104317684 @default.
- W2040209654 hasConceptScore W2040209654C142724271 @default.
- W2040209654 hasConceptScore W2040209654C169760540 @default.
- W2040209654 hasConceptScore W2040209654C24586158 @default.
- W2040209654 hasConceptScore W2040209654C24998067 @default.
- W2040209654 hasConceptScore W2040209654C2776925932 @default.
- W2040209654 hasConceptScore W2040209654C2777348757 @default.
- W2040209654 hasConceptScore W2040209654C2778373776 @default.
- W2040209654 hasConceptScore W2040209654C2779134260 @default.
- W2040209654 hasConceptScore W2040209654C2780596555 @default.
- W2040209654 hasConceptScore W2040209654C2781041448 @default.
- W2040209654 hasConceptScore W2040209654C28859421 @default.
- W2040209654 hasConceptScore W2040209654C501734568 @default.
- W2040209654 hasConceptScore W2040209654C54355233 @default.
- W2040209654 hasConceptScore W2040209654C71924100 @default.
- W2040209654 hasConceptScore W2040209654C86803240 @default.
- W2040209654 hasIssue "11" @default.
- W2040209654 hasLocation W20402096541 @default.
- W2040209654 hasLocation W20402096542 @default.
- W2040209654 hasOpenAccess W2040209654 @default.
- W2040209654 hasPrimaryLocation W20402096541 @default.
- W2040209654 hasRelatedWork W1535445163 @default.
- W2040209654 hasRelatedWork W2030012691 @default.
- W2040209654 hasRelatedWork W2044008811 @default.
- W2040209654 hasRelatedWork W2051438294 @default.
- W2040209654 hasRelatedWork W2063230836 @default.
- W2040209654 hasRelatedWork W2067841959 @default.
- W2040209654 hasRelatedWork W2085368083 @default.
- W2040209654 hasRelatedWork W2098526078 @default.
- W2040209654 hasRelatedWork W3208343344 @default.
- W2040209654 hasRelatedWork W2608654997 @default.
- W2040209654 hasVolume "11" @default.
- W2040209654 isParatext "false" @default.
- W2040209654 isRetracted "false" @default.
- W2040209654 magId "2040209654" @default.
- W2040209654 workType "article" @default.