Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040222557> ?p ?o ?g. }
- W2040222557 endingPage "7245" @default.
- W2040222557 startingPage "7238" @default.
- W2040222557 abstract "ABSTRACT Corynebacterium glutamicum grew on resorcinol as a sole source of carbon and energy. By genome-wide data mining, two gene clusters, designated NCgl1110-NCgl1113 and NCgl2950-NCgl2953, were proposed to encode putative proteins involved in resorcinol catabolism. Deletion of the NCgl2950-NCgl2953 gene cluster did not result in any observable phenotype changes. Disruption and complementation of each gene at NCgl1110-NCgl1113, NCgl2951, and NCgl2952 indicated that these genes were involved in resorcinol degradation. Expression of NCgl1112, NCgl1113, and NCgl2951 in Escherichia coli revealed that NCgl1113 and NCgl2951 both coded for hydroxyquinol 1,2-dioxygenases and NCgl1112 coded for maleylacetate reductases. NCgl1111 encoded a putative monooxygenase, but this putative hydroxylase was very different from previously functionally identified hydroxylases. Cloning and expression of NCgl1111 in E. coli revealed that NCgl1111 encoded a resorcinol hydroxylase that needs NADPH as a cofactor. E. coli cells containing Ncgl1111 and Ncgl1113 sequentially converted resorcinol into maleylacetate. NCgl1110 and NCgl2950 both encoded putative TetR family repressors, but only NCgl1110 was transcribed and functional. NCgl2953 encoded a putative transporter, but disruption of this gene did not affect resorcinol degradation by C. glutamicum . The function of NCgl2953 remains unclear." @default.
- W2040222557 created "2016-06-24" @default.
- W2040222557 creator A5009810201 @default.
- W2040222557 creator A5022714913 @default.
- W2040222557 creator A5042999279 @default.
- W2040222557 creator A5052282150 @default.
- W2040222557 creator A5060733684 @default.
- W2040222557 creator A5080777603 @default.
- W2040222557 date "2006-11-01" @default.
- W2040222557 modified "2023-10-03" @default.
- W2040222557 title "Genetic Characterization of the Resorcinol Catabolic Pathway in <i>Corynebacterium glutamicum</i>" @default.
- W2040222557 cites W140064010 @default.
- W2040222557 cites W1544883620 @default.
- W2040222557 cites W1548521778 @default.
- W2040222557 cites W1573769735 @default.
- W2040222557 cites W1840669791 @default.
- W2040222557 cites W1877355868 @default.
- W2040222557 cites W1877788388 @default.
- W2040222557 cites W1934318147 @default.
- W2040222557 cites W1970712032 @default.
- W2040222557 cites W1972295797 @default.
- W2040222557 cites W1998591058 @default.
- W2040222557 cites W2009776924 @default.
- W2040222557 cites W2010984666 @default.
- W2040222557 cites W2015500420 @default.
- W2040222557 cites W2018342225 @default.
- W2040222557 cites W2030265152 @default.
- W2040222557 cites W2044694678 @default.
- W2040222557 cites W2064825632 @default.
- W2040222557 cites W2072278470 @default.
- W2040222557 cites W2073241921 @default.
- W2040222557 cites W2083504366 @default.
- W2040222557 cites W2108487003 @default.
- W2040222557 cites W2111204389 @default.
- W2040222557 cites W2111929724 @default.
- W2040222557 cites W2128585170 @default.
- W2040222557 cites W2128635872 @default.
- W2040222557 cites W2151706268 @default.
- W2040222557 cites W2153076508 @default.
- W2040222557 cites W2169610308 @default.
- W2040222557 cites W2171535756 @default.
- W2040222557 cites W4293247451 @default.
- W2040222557 doi "https://doi.org/10.1128/aem.01494-06" @default.
- W2040222557 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1636210" @default.
- W2040222557 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16963551" @default.
- W2040222557 hasPublicationYear "2006" @default.
- W2040222557 type Work @default.
- W2040222557 sameAs 2040222557 @default.
- W2040222557 citedByCount "41" @default.
- W2040222557 countsByYear W20402225572012 @default.
- W2040222557 countsByYear W20402225572013 @default.
- W2040222557 countsByYear W20402225572014 @default.
- W2040222557 countsByYear W20402225572015 @default.
- W2040222557 countsByYear W20402225572016 @default.
- W2040222557 countsByYear W20402225572017 @default.
- W2040222557 countsByYear W20402225572019 @default.
- W2040222557 countsByYear W20402225572020 @default.
- W2040222557 countsByYear W20402225572023 @default.
- W2040222557 crossrefType "journal-article" @default.
- W2040222557 hasAuthorship W2040222557A5009810201 @default.
- W2040222557 hasAuthorship W2040222557A5022714913 @default.
- W2040222557 hasAuthorship W2040222557A5042999279 @default.
- W2040222557 hasAuthorship W2040222557A5052282150 @default.
- W2040222557 hasAuthorship W2040222557A5060733684 @default.
- W2040222557 hasAuthorship W2040222557A5080777603 @default.
- W2040222557 hasBestOaLocation W20402225571 @default.
- W2040222557 hasConcept C104317684 @default.
- W2040222557 hasConcept C127716648 @default.
- W2040222557 hasConcept C150194340 @default.
- W2040222557 hasConcept C158448853 @default.
- W2040222557 hasConcept C178790620 @default.
- W2040222557 hasConcept C181199279 @default.
- W2040222557 hasConcept C185592680 @default.
- W2040222557 hasConcept C188082640 @default.
- W2040222557 hasConcept C2776260651 @default.
- W2040222557 hasConcept C2777274385 @default.
- W2040222557 hasConcept C2780016452 @default.
- W2040222557 hasConcept C36857842 @default.
- W2040222557 hasConcept C54355233 @default.
- W2040222557 hasConcept C547475151 @default.
- W2040222557 hasConcept C55493867 @default.
- W2040222557 hasConcept C86803240 @default.
- W2040222557 hasConcept C96942376 @default.
- W2040222557 hasConceptScore W2040222557C104317684 @default.
- W2040222557 hasConceptScore W2040222557C127716648 @default.
- W2040222557 hasConceptScore W2040222557C150194340 @default.
- W2040222557 hasConceptScore W2040222557C158448853 @default.
- W2040222557 hasConceptScore W2040222557C178790620 @default.
- W2040222557 hasConceptScore W2040222557C181199279 @default.
- W2040222557 hasConceptScore W2040222557C185592680 @default.
- W2040222557 hasConceptScore W2040222557C188082640 @default.
- W2040222557 hasConceptScore W2040222557C2776260651 @default.
- W2040222557 hasConceptScore W2040222557C2777274385 @default.
- W2040222557 hasConceptScore W2040222557C2780016452 @default.
- W2040222557 hasConceptScore W2040222557C36857842 @default.
- W2040222557 hasConceptScore W2040222557C54355233 @default.
- W2040222557 hasConceptScore W2040222557C547475151 @default.
- W2040222557 hasConceptScore W2040222557C55493867 @default.