FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040235764> ?p ?o ?g. }

• W2040235764 endingPage "1163" @default.
• W2040235764 startingPage "1147" @default.
• W2040235764 abstract "This study evaluates the dose-response relationship for inhalation exposure to hexavalent chromium [Cr(VI)] and lung cancer mortality for workers of a chromate production facility, and provides estimates of the carcinogenic potency. The data were analyzed using relative risk and additive risk dose-response models implemented with both Poisson and Cox regression. Potential confounding by birth cohort and smoking prevalence were also assessed. Lifetime cumulative exposure and highest monthly exposure were the dose metrics evaluated. The estimated lifetime additional risk of lung cancer mortality associated with 45 years of occupational exposure to 1 μg/m3 Cr(VI) (occupational exposure unit risk) was 0.00205 (90%CI: 0.00134, 0.00291) for the relative risk model and 0.00216 (90%CI: 0.00143, 0.00302) for the additive risk model assuming a linear dose response for cumulative exposure with a five-year lag. Extrapolating these findings to a continuous (e.g., environmental) exposure scenario yielded an environmental unit risk of 0.00978 (90%CI: 0.00640, 0.0138) for the relative risk model [e.g., a cancer slope factor of 34 (mg/kg-day)−1] and 0.0125 (90%CI: 0.00833, 0.0175) for the additive risk model. The relative risk model is preferred because it is more consistent with the expected trend for lung cancer risk with age. Based on statistical tests for exposure-related trend, there was no statistically significant increased lung cancer risk below lifetime cumulative occupational exposures of 1.0 mg-yr/m3, and no excess risk for workers whose highest average monthly exposure did not exceed the current Permissible Exposure Limit (52 μg/m3). It is acknowledged that this study had limited power to detect increases at these low exposure levels. These cancer potency estimates are comparable to those developed by U.S. regulatory agencies and should be useful for assessing the potential cancer hazard associated with inhaled Cr(VI)." @default.
• W2040235764 created "2016-06-24" @default.
• W2040235764 creator A5009211568 @default.
• W2040235764 creator A5024447291 @default.
• W2040235764 creator A5025673332 @default.
• W2040235764 creator A5042507412 @default.
• W2040235764 creator A5052737783 @default.
• W2040235764 creator A5056823527 @default.
• W2040235764 creator A5068592561 @default.
• W2040235764 creator A5083865206 @default.
• W2040235764 creator A5086602297 @default.
• W2040235764 date "2003-12-01" @default.
• W2040235764 modified "2023-09-26" @default.
• W2040235764 title "Dose‐Response and Risk Assessment of Airborne Hexavalent Chromium and Lung Cancer Mortality" @default.
• W2040235764 cites W1551604617 @default.
• W2040235764 cites W1967831570 @default.
• W2040235764 cites W1976959980 @default.
• W2040235764 cites W1986219410 @default.
• W2040235764 cites W2012837757 @default.
• W2040235764 cites W2021267738 @default.
• W2040235764 cites W2058906081 @default.
• W2040235764 cites W2068825026 @default.
• W2040235764 cites W2073565251 @default.
• W2040235764 cites W2080485663 @default.
• W2040235764 cites W2082757332 @default.
• W2040235764 cites W2084368735 @default.
• W2040235764 cites W2087403496 @default.
• W2040235764 cites W2093116239 @default.
• W2040235764 cites W2104510909 @default.
• W2040235764 cites W2105426204 @default.
• W2040235764 cites W2107223440 @default.
• W2040235764 cites W2118587617 @default.
• W2040235764 cites W2148852984 @default.
• W2040235764 cites W2159969974 @default.
• W2040235764 cites W2168499629 @default.
• W2040235764 cites W2316212352 @default.
• W2040235764 cites W2328335699 @default.
• W2040235764 cites W4245958676 @default.
• W2040235764 cites W44278768 @default.
• W2040235764 doi "https://doi.org/10.1111/j.0272-4332.2003.00388.x" @default.
• W2040235764 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14641890" @default.
• W2040235764 hasPublicationYear "2003" @default.
• W2040235764 type Work @default.
• W2040235764 sameAs 2040235764 @default.
• W2040235764 citedByCount "47" @default.
• W2040235764 countsByYear W20402357642012 @default.
• W2040235764 countsByYear W20402357642013 @default.
• W2040235764 countsByYear W20402357642014 @default.
• W2040235764 countsByYear W20402357642015 @default.
• W2040235764 countsByYear W20402357642016 @default.
• W2040235764 countsByYear W20402357642017 @default.
• W2040235764 countsByYear W20402357642018 @default.
• W2040235764 countsByYear W20402357642019 @default.
• W2040235764 countsByYear W20402357642020 @default.
• W2040235764 countsByYear W20402357642021 @default.
• W2040235764 countsByYear W20402357642022 @default.
• W2040235764 crossrefType "journal-article" @default.
• W2040235764 hasAuthorship W2040235764A5009211568 @default.
• W2040235764 hasAuthorship W2040235764A5024447291 @default.
• W2040235764 hasAuthorship W2040235764A5025673332 @default.
• W2040235764 hasAuthorship W2040235764A5042507412 @default.
• W2040235764 hasAuthorship W2040235764A5052737783 @default.
• W2040235764 hasAuthorship W2040235764A5056823527 @default.
• W2040235764 hasAuthorship W2040235764A5068592561 @default.
• W2040235764 hasAuthorship W2040235764A5083865206 @default.
• W2040235764 hasAuthorship W2040235764A5086602297 @default.
• W2040235764 hasConcept C120195587 @default.
• W2040235764 hasConcept C12174686 @default.
• W2040235764 hasConcept C126322002 @default.
• W2040235764 hasConcept C151032500 @default.
• W2040235764 hasConcept C178790620 @default.
• W2040235764 hasConcept C185592680 @default.
• W2040235764 hasConcept C2776256026 @default.
• W2040235764 hasConcept C2781468121 @default.
• W2040235764 hasConcept C2908647359 @default.
• W2040235764 hasConcept C33070731 @default.
• W2040235764 hasConcept C38652104 @default.
• W2040235764 hasConcept C41008148 @default.
• W2040235764 hasConcept C44249647 @default.
• W2040235764 hasConcept C50382708 @default.
• W2040235764 hasConcept C511782168 @default.
• W2040235764 hasConcept C71924100 @default.
• W2040235764 hasConcept C73269764 @default.
• W2040235764 hasConcept C77350462 @default.
• W2040235764 hasConcept C82789193 @default.
• W2040235764 hasConcept C86803240 @default.
• W2040235764 hasConcept C99454951 @default.
• W2040235764 hasConceptScore W2040235764C120195587 @default.
• W2040235764 hasConceptScore W2040235764C12174686 @default.
• W2040235764 hasConceptScore W2040235764C126322002 @default.
• W2040235764 hasConceptScore W2040235764C151032500 @default.
• W2040235764 hasConceptScore W2040235764C178790620 @default.
• W2040235764 hasConceptScore W2040235764C185592680 @default.
• W2040235764 hasConceptScore W2040235764C2776256026 @default.
• W2040235764 hasConceptScore W2040235764C2781468121 @default.
• W2040235764 hasConceptScore W2040235764C2908647359 @default.
• W2040235764 hasConceptScore W2040235764C33070731 @default.
• W2040235764 hasConceptScore W2040235764C38652104 @default.

• next