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- W2040245860 abstract "We study the evolution of the rate of self-fertilization in response to deleterious mutations at multiple loci. Although partial selfing induces associations among loci even in the absence of linkage, associations among mutations at different loci are of a smaller order of magnitude than the mutation rate. Genotypes that carry homozygous lethal mutations in heterozygous form at i loci occur in frequencies of the order (Ti) μi, in which T denotes the number of viability loci and μ the mutation rate. While associations between mutations at different loci remain small even under inbreeding, each viability locus develops an association with the modifier of the rate of self-fertilization that substantially affects the evolution of the breeding system. Positive associations between enhancers of selfing and haplotypes carrying multiple wild-type alleles and positive associations in heterozygosity between the modifier locus and the viability loci promote evolutionary increases in the rate of self-fertilization." @default.
- W2040245860 created "2016-06-24" @default.
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- W2040245860 date "1991-10-01" @default.
- W2040245860 modified "2023-10-17" @default.
- W2040245860 title "Coevolution of self-fertilization and inbreeding depression. III. Homozygous lethal mutations at multiple loci" @default.
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- W2040245860 doi "https://doi.org/10.1016/0040-5809(91)90052-h" @default.
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