Matches in SemOpenAlex for { <https://semopenalex.org/work/W2040251963> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W2040251963 endingPage "307" @default.
- W2040251963 startingPage "301" @default.
- W2040251963 abstract "A randomized single-blind study of the effects of erythromycin and roxithromycin on chlamydial conjunctivitis was performed on a group of patients, comprising 28 newborns and 27 adults. Treatment used was either 200 mg of erythromycin ethylsuccinate or 50 mg of roxithromycin daily, divided into two doses for the neonatal group or for the adult group, 1000 mg of erythromycin stearate or 300 mg of roxithromycin daily divided into two doses. All patients were treated for ten days. Clinically nine of the neonates and 13 of the adults had unilateral conjunctivitis, whilst the remaining cases were bilateral. At follow-up one month after commencing therapy, all but one (erythromycin-treated) of the 28 neonates and three (two of whom were erythromycin-treated) of the 27 adults were cured. However, 16 (nine neonates and seven adults) were culture-positive for Chlamydia trachomatis in samples from eye and/or nasopharynx. The culture-positive group comprised ten cases (four neonates and six adults) who had been treated with erythromycin and six (five neonates and one adult) with roxithromycin. No major side effects of the therapy were seen. The study indicates that there was no difference in the clinical cure rate for the two drugs either in neonates or in adults. However, the isolation rate of chlamydiae in the adult group differed, with 12 (92%) of the 13 roxithromycin-treated cases becoming culture-negative, whilst this was true for only eight (57%) of the 14 erythromycin-treated cases (P less than 0.007)." @default.
- W2040251963 created "2016-06-24" @default.
- W2040251963 creator A5000488837 @default.
- W2040251963 creator A5071421734 @default.
- W2040251963 date "1991-01-01" @default.
- W2040251963 modified "2023-10-16" @default.
- W2040251963 title "Treatment of chlamydial conjunctivitis in newborns and adults with erythromycin and roxithromycin" @default.
- W2040251963 doi "https://doi.org/10.1093/jac/28.2.301" @default.
- W2040251963 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1778860" @default.
- W2040251963 hasPublicationYear "1991" @default.
- W2040251963 type Work @default.
- W2040251963 sameAs 2040251963 @default.
- W2040251963 citedByCount "14" @default.
- W2040251963 countsByYear W20402519632013 @default.
- W2040251963 countsByYear W20402519632017 @default.
- W2040251963 countsByYear W20402519632018 @default.
- W2040251963 countsByYear W20402519632020 @default.
- W2040251963 crossrefType "journal-article" @default.
- W2040251963 hasAuthorship W2040251963A5000488837 @default.
- W2040251963 hasAuthorship W2040251963A5071421734 @default.
- W2040251963 hasConcept C126322002 @default.
- W2040251963 hasConcept C203014093 @default.
- W2040251963 hasConcept C2778423520 @default.
- W2040251963 hasConcept C2780122209 @default.
- W2040251963 hasConcept C2780206985 @default.
- W2040251963 hasConcept C3019249092 @default.
- W2040251963 hasConcept C501593827 @default.
- W2040251963 hasConcept C71924100 @default.
- W2040251963 hasConcept C86803240 @default.
- W2040251963 hasConcept C89423630 @default.
- W2040251963 hasConcept C90924648 @default.
- W2040251963 hasConceptScore W2040251963C126322002 @default.
- W2040251963 hasConceptScore W2040251963C203014093 @default.
- W2040251963 hasConceptScore W2040251963C2778423520 @default.
- W2040251963 hasConceptScore W2040251963C2780122209 @default.
- W2040251963 hasConceptScore W2040251963C2780206985 @default.
- W2040251963 hasConceptScore W2040251963C3019249092 @default.
- W2040251963 hasConceptScore W2040251963C501593827 @default.
- W2040251963 hasConceptScore W2040251963C71924100 @default.
- W2040251963 hasConceptScore W2040251963C86803240 @default.
- W2040251963 hasConceptScore W2040251963C89423630 @default.
- W2040251963 hasConceptScore W2040251963C90924648 @default.
- W2040251963 hasIssue "2" @default.
- W2040251963 hasLocation W20402519631 @default.
- W2040251963 hasLocation W20402519632 @default.
- W2040251963 hasOpenAccess W2040251963 @default.
- W2040251963 hasPrimaryLocation W20402519631 @default.
- W2040251963 hasRelatedWork W1938435819 @default.
- W2040251963 hasRelatedWork W2003008769 @default.
- W2040251963 hasRelatedWork W2025003208 @default.
- W2040251963 hasRelatedWork W2027191482 @default.
- W2040251963 hasRelatedWork W2100679596 @default.
- W2040251963 hasRelatedWork W2116733702 @default.
- W2040251963 hasRelatedWork W2136132262 @default.
- W2040251963 hasRelatedWork W2163102356 @default.
- W2040251963 hasRelatedWork W2170087676 @default.
- W2040251963 hasRelatedWork W77384733 @default.
- W2040251963 hasVolume "28" @default.
- W2040251963 isParatext "false" @default.
- W2040251963 isRetracted "false" @default.
- W2040251963 magId "2040251963" @default.
- W2040251963 workType "article" @default.