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- W2040258575 abstract "Objective: to report two cases of resistance to thyroid hormone to increase the awareness of this syndrome, which is frequently isdiagnosed and incorrectly treated. CORRESPONDENCE TO: Methods: we described two siblings, both of whom were diagnosed as having thyrotoxicosis and one of them was treated with carbamazole and subsequently developed hypothyroidism. Both patients showed features of resistance to thyroid hormone and required additional L-thyroxine to normalize the thyroid stimulating hormone level while remaining clinically euthyroid. Results: Laboratory evaluation revealed increased serum thyroxine and tri-iodothyroxine levels as well as increased thyroid stimulating hormone (TSH) levels. The free alpha subunit/TSH ratio was normal, and CT of the pituitary gland showed no tumour. Metabolic studies using graded doses of tri-iodothyroxine supported the diagnosis. 4) Dr. Elamin A, E-mail: azizmin@gmail.com" @default.
- W2040258575 created "2016-06-24" @default.
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- W2040258575 date "2007-07-25" @default.
- W2040258575 modified "2023-09-23" @default.
- W2040258575 title "The syndrome of resistance to Thyroid Hormone, Misdiagnosed as thyrotoxicosis" @default.
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- W2040258575 doi "https://doi.org/10.4314/sjms.v2i1.50401" @default.
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