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• W2040272472 abstract "Highly efficient one-pot syntheses of antiproliferative 9-aminoacridine (9-AA) derivatives are described. Simple SNAr and addition/elimination reactions, using readily accessible starting materials, give a fast entry to novel 9-(pyridylamino)acridines, 9-(pyrimidinylamino)acridines and potential “dual-function” bioreductive 9-(acridinylamino)quinone intercalators. The synthetic routes reported in this work are general and readily applicable, significantly expanding the range and scope of potential 9-AA anticancer candidates." @default.
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• W2040272472 date "2011-05-27" @default.
• W2040272472 modified "2023-09-27" @default.
• W2040272472 title "One-Pot Synthesis of Novel Antiproliferative 9-Aminoacridines" @default.
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• W2040272472 doi "https://doi.org/10.1002/ejoc.201100133" @default.
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